Tissue Engineering Principles and Practices

Tissue engineering research continues to captivate the interest of researchers and the general public alike. Popular media outlets like The New York Times, Time, and Wired continue to engage a wide audience and foster excitement for the field as regenerative medicine inches toward becoming a clinical reality. Putting the numerous advances in the field into a broad context, Tissue Engineering: Principles and Practices explores current thoughts on the development of engineered tissues. With contributions from experts and pioneers, this book begins with coverage of the fundamentals, details the supporting technology, and then elucidates their applications in tissue engineering. It explores strategic directions, nanobiomaterials, biomimetics, gene therapy, cell engineering, and more. The chapters then explore the applications of these technologies in areas such as bone engineering, cartilage tissue, dental tissue, vascular engineering, and neural engineering.A comprehensive overview of major research topics in tissue engineering, the book: Examines the properties of stem cells, primary cells, growth factors, and extracellular matrix as well as their impact on the development of tissue-engineered devices Focuses upon those strategies typically incorporated into tissue-engineered devices or utilized in their development, including scaffolds, nanocomposites, bioreactors, drug delivery systems, and gene therapy techniques Presents synthetic tissues and organs that are currently under development for regenerative medicine applications The contributing authors are a diverse group with backgrounds in academia, clinical medicine, and industry. Furthermore, this book includes contributions from Europe, Asia, and North America, helping to broaden the views on the development and application of tissue-engineered devices. The book provides a useful reference for courses devoted to tissue engineering fundamentals and those laboratories developing tissue-engineered devices for regenerative medicine therapy.

FundamentalsStrategic Directions, Peter C. JohnsonSilks, Monica A. Serban and David L. KaplanCalcium Phosphates, Kemal Sariibrahimoglu, Joop G.C. Wolke, Sander C.G. Leeuwenburgh, and John A. JansenEngineered Protein Biomaterials, Andreina Parisi-Amon and Sarah C. HeilshornSynthetic Biomaterials, Joshua S. Katz and Jason A. BurdickGrowth Factors and Morphogens: Signals for Tissue Engineering, A. Hari ReddiSignal Expression, Martha O. Wang and John P. FisherPluripotent Stem Cells, Todd C. McDevitt and Mellissa A. KinneyHematopoietic Stem Cells, Ian M. Kaplan, Sebastien Morisot, and Curt I. CivinMesenchymal Stem Cells, Pamela C. Yelick and Weibo ZhangEnabling TechnologiesNanobiomaterials for Tissue Engineering, Pramod K. Avti, Sunny C. Patel, Pushpinder Uppal, Grace O’Malley, Joseph Garlow, and Balaji SitharamanBiomimetic Approaches in Tissue Engineering, Indong Jun, Min Sup Kim, Ji-Hye Lee, Young Min Shin, and Heungsoo ShinMolecular Biology Techniques, X.G. Chen, Y.L. Fang, and W.T. GodbeyBiomaterial Mechanics, Kimberly M. Stroka, Leann L. Norman, and Helim Aranda-EspinozaMechanical Conditioning, Elaine L. Lee and Horst A. von RecumMicropatterned Biomaterials for Cell and Tissue Engineering, Murugan Ramalingam and Ali KhademhosseiniDrug Delivery, Prinda Wanakule and Krishnendu RoyGene Therapy, Abhay Pandit, C. Holladay, M. Kulkarni, and W. MinorNanotechnology-Based Cell Engineering Strategies for Tissue Engineering and Regenerative Medicine Applications, Joaquim Miguel Oliveira, João Filipe Mano, and Rui Luís ReisCell Encapsulation, Stephanie J. BryantCoculture Systems for Mesenchymal Stem Cells, Song P. Seto and Johnna S. TemenoffTissue Engineering Bioreactors, Sarindr Bhumiratana, Elisa Cimetta, Nina Tandon, Warren Grayson, Milica Radisic, and Gordana Vunjak-NovakovicShear Forces, Jose F. Alvarez-Barreto, Samuel B. VanGordon, Brandon W. Engebretson, and Vasillios I. SikavitsasVascularization of Engineered Tissues, Monica L. Moya and Eric M. BreyBiomedical Imaging of Engineered Tissues, Nicholas E. Simpson and Athanassios SambanisMultiscale Modeling of In Vitro Tissue Cultivation, Kyriacos ZygourakisApplicationsBone Engineering, Lucas A. Kinard, Antonios G. Mikos, and F. Kurtis KasperDental and Craniofacial Bioengineering, Hemin Nie and Jeremy J. MaoTendon and Ligament Engineering, Nicholas Sears, Tyler Touchet, Hugh Benhardt, and Elizabeth Cosgriff-HernándezCartilage Tissue Engineering, Emily E. Coates and John P. FisherTMJ Engineering, Michael S. DetamoreInterface Tissue Engineering, Helen H. Lu, Nora Khanarian, Kristen Moffat, and Siddarth SubramonyThe Bioengineering of Dental Tissues, Rena N. D’Souza, Katherine R. Regan, Kerstin M. Galler, and Songtao ShiTissue Engineering of the Urogenital System, In Kap Ko, Anthony Atala, and James J. YooVascular Tissue Engineering, Laura J. SuggsNeural Engineering, Yen-Chih Lin and Kacey G. MarraTumor Engineering: Applications for Cancer Biology and Drug Development, Joseph A. Ludwig and Emily BurdettIndex