Sex/Gender-Specific Medicine in the Gastrointestinal Diseases

Sex/gender - specific medicine (SGM) is defined as the practice of medicine based on the understanding that biology and social roles are important in men and women for disease prevention, screening, diagnosis, and treatment. Current research demonstrates differences in disease incidence, symptomatology, morbidity, and mortality based on sex and gender. Sex/gender-specific medicine is a fundamental aspect of tailored therapy and precision medicine. Therefore, the variables must be considered in medical education and practice as well as in research models ranging from human participants, animals and cells. Gastroenterology is very big and important division of Internal Medicine, which include esophagus, stomach, small and large intestine, pancreatobiliary tract and liver. Nowadays estrogen is known to play a key role in the prevention of colon cancer and progression of liver cirrhosis and hepatocellular carcinoma, especially in women. This book covers the sex/gender-specific medicine inthe area of gastrointestinal (GI) tract in the adults as well as in the pediatrics and in the gut microbiota.

1.Sex/gender-specific medicine.- 2.The difference of sex and gender in the gastrointestinal diseases.- 3.The metabolism of estrogen and testosteron.- 4.Esophagus.- 5.Stomach.- 6.Pancreas and biliary diseases.- 7.Liver.- 8. Colon.- 9. Brain-Gut-Microbiome axis.- 10. Sex difference of gut microbiota.- 11. Overlap syndrome of FGIDs (functional gastrointestinal disorders).- 12. Sex difference of gastrointestinal diseases in the pediatrics.- 13. Pharmacodynamics and Pharmacokinetics of gastrointestinal drugs.- 14. Sex/gender-specific medicine education and work-l ife conflict and its health effects on Korean gastroenterologists according to age and sex.

Dr Nayoung Kim worked at Membrane Biology Laboratory, UCLA Medical School, USA as a Research Scholar (1999-2002). She is working as a professor at the Seoul National University Bundang Hospital as well as Seoul National University, College of Medicine in Seoul since 2013. Her research focuses on the sex- and -gender specific medicine, functional dyspepsia, various aspects of Helicobacter pylori, gastroesohageal reflux disease, microbiota and age-dependent change of GI organ with its function. She also actively participates in the Korean Academic Society activities and worked as a deputy editor of J Neurogastroenterol Motil from Jan. 2010 till April 2015 and a Congress Chairwoman of Korean Society of Neurogastroenterology and Motility from April 2015 till April 2017. She was Vice President of Korea Federation of Women Science and Technology Association (KOFWST) from Jan. 2018 till Jan. 2020. She has about 230 SCI publications in the various GI areas as a first author or corresponding author and the citation number was 21,690 times (goggle November 2021). She received Marshall Warren Lectureship Award in 2018 at APDW 2018.