Introduction: History of the Cultivation and Use of Sesame, D. BedigianCultivated Sesame, and Wild Relatives in the Genus Sesamum L, D. Bedigian Chemical Studies on the Lignans and Other Minor Constituents of Sesame Seed Oil, A.Kamal-EldinSesame Seed Coat:A Rich Source of Potential Mammalian Lignan Pprecursors, R. Grougnet, P. Magiatis, S. Mitakou, and A.-L. SkaltsounisAntioxidant and Anti-Carcinogenic Potentials of Sesame Lignans, D.H.F. Mak, P.Y. Chiu, and K.M. KoSesame Seed and Its Lignans: Metabolism and Bioactivities, S.M. Sacco and L.U. ThompsonPhysiological Effects of Sesame: Bioactive and Antioxidant Compounds, F. Shahidi and Z. TanSesame Seed Food Allergy, S.S. TeuberFlavor Constituents of Sesame, F. Shahidi, T. Hughes, and Z. TanSeed Oil Bodies of Sesame and Their Surface Proteins, Oleosin, Caleosin, and Steroleosin, J.T.C. TzenUse of Near-Infrared Reflectance Spectroscopy for Nondestructive Analyses of Sesame, T. Sato, A.A. Maw, and M. KatsutaSesame’s Protective Role in Crop Nematode Control, G.A. Elbadri and A.M. YassinMolecular Biotechnology of Sesame, M.C. Suh and C.-H. ChungResponses of Sesame to Plant Growth Regulators, Micronutrients and Salinity, M. PrakashSeed Genetics in Relation to Yield in Sesame, S. Thirugnana KumarSesame Diseases and Their Management, P. Narayanasamy Sesame Cultivation and Use in China, Z. YingzhongSesame Cultivation and Use in Ethiopia, A. Teklewold, T. Made, and T. BayeSesame Cultivation and Use in Iran, S.M. Mahdi Mortazavian and J.A. Kohpayegani Sesame Cultivation and Use in Somalia, A.Y. Sidow Sesame Cultivation and Use in Thailand, W. WongyaiSesame Cultivation and Use in Turkey, B. UzunSesame Cultivation and Irrigation in the Kingdom of Urartu (Ararat), Armenian Highlands, and Its Aftermath: Major Agricultural Innovation, D. Bedigian Introduction and Early Use of Sesame in America: Medicine, Cookery and Folkways, D. Bedigian Current Market Trends: Progress, Expansion, and Economic Importance of Sesame, D. Bedigian Current Regulatory Status of Sesame and Its Commercial Products, D. Bedigian