Oxford Textbook of Axial Spondyloarthritis

Axial Spondyloarthritis is a timely addition to the Oxford Textbooks in Rheumatology series, providing a comprehensive reference to this rapidly evolving field. The conceptual framework of the disease has now evolved beyond ankylosing spondylitis to encompass a broader concept of axial inflammation. Earlier recognition has opened the door to earlier intervention, and the understanding of the biologic basis of axial SpA has seen significant advances in recent years. The first textbook to cover axial spondyloarthritis in this level of detail from a global perspective, this volume offers a practical and complete resource compiled by a multidisciplinary and multinational team of experts. Beginning with a historical perspective on the disease, the textbook provides a comprehensive background in the epidemiology, diagnosis, and classification of axial spondyloarthritis. Immune mechanisms and genetics are covered, along with imaging and a detailed section on the range of treatments options currently available. A section on extra-articular manifestations provides a comprehensive knowledge base for the clinician treating patients with spondyloarthritis, and chapters on the economics of the disease, physical functioning, and patient registries complete the broad coverage of the topic. Practical, easy to use, yet detailed with respect to pathophysiology, diagnostics, and management, this textbook provides a comprehensive reference for rheumatologists, general practitioners, internists, and paediatricians managing patients with axial spondyloarthritis.

1 - Spondyloarthritis in antiquity and in history
2 - Epidemiology of Axial Spondyloarthritis
3 - Diagnosis and classification of Axial Spondyloarthritis
4 - Diagnosis, classification, and management of Peripheral Spondyloarthritis
5 - Genetics of Spondyloarthritis
6 - Immune mechanisms: HLA-B27
7 - Immune mechanisms: Innate immunity
8 - Immune mechanisms: Adaptive immunity
9 - Infection and Spondyloarthritis
10 - Pathology: Bone
11 - Clinical features
12 - Clinical outcomes
13 - Imaging: Sacroiliac joints
14 - Imaging: Spine
15 - Juvenile-onset Spondyloarthritis
16 - Extra-articular manifestations: Uveitis
17 - Extra-articula manifestations: Inflammatory Bowel Disease
18 - Extra-articular manifestations: Psoriasis
19 - Treatment: Non-pharmacological
20 - Treatment: Non-Steroidal Anti-inflammatory Drugs in Axial Spondyloarthritis
21 - Treatment: DMARDS
22 - Treatment: Biologics
23 - Treatment: Aim and indication of surgical treatment
24 - Patient registries
25 - Economic evaluation of diagnosing and treating axial SpA
26 - Physical functioning and work ability
27 - Patient support and advocacy in Axial Spondyloarthritis
28 - Axial Spondyloarthritis in Asia
29 - Axial Spondyloarthritis in Latin America
30 - Axial Spondyloarthritis in India

Robert D. Inman completed his undergraduate degree at Yale University, and his medical degree at McMaster University. He did his training in Internal Medicine at Vanderbilt University and his fellowship in Rheumatology at Cornell University, based at the Hospital for Special Surgery. He worked as a research fellow at the Hammersmith Hospital in London, then was appointed Assistant Professor of Medicine at Cornell University. He moved to the University of Toronto where he was appointed Professor in the Departments of Medicine and Immunology. He was Director of Rheumatology at the University of Toronto 1991-2002. Dr Inman is currently Director of the Arthritis Center of Excellence at the University Health Network, Director of the Spondylitis Program at Toronto Western Hospital, and Deputy Physician in Chief, Research at University Health Network. Joachim Sieper is Head of the Department of Rheumatology at the Charite University Hospital, Berlin, Germany. Prof. Sieper was a Full member of the Medicines Commission 2002-2010, and has been an Extraordinary member of the Drug Commission since 2011.