Professor John B. Saunders MA, MB BChir, MD, FRCP, FRACP, FAChAM, FAFPHM is a Professor and Consultant Physician in Internal Medicine and Addiction Medicine, with appointments at the Universities of Queensland and Sydney in Australia. He graduated in pharmacology and medicine from the University of Cambridge and undertook specialist medical training in internal medicine, gastroenterology, and addiction medicine. His career as a clinician, service director, and researcher in addictive disorders dates back over 40 years. He has been a member of many government committees, including the Australian National Council on Drugs. He has worked with the WHO since 1981 and responsible for developing the AUDIT Questionnaire. He is a member of the WHO's Expert Advisory Panel on Substance Abuse and the ICD-11 Substance-Related and Addictive Disorders Workgroup. He is President-Elect of the Australasian Chapter of Addiction Medicine. He has published 6 books and 400 scientific papers, reviews, and book chapters. Professor David J. Nutt MA, MB BChir, DM, FRCP, FRCPsych, FMedSci is Professor of Psychopharmacology at the Department of Medicine, Imperial College. He graduated from the University of Cambridge and completed his medical training at Guy's Hospital. After completing this he became Wellcome Senior Fellow in Psychiatry. He then spent two years as Chief of the Section of Clinical Science in the US National Institute of Alcohol Abuse and Alcoholism. In 1988 he set up the Psychopharmacology Unit at Bristol University, where he became Dean of Clinical Medicine, before moving to Imperial College in 2008. He has held presidencies of the European Brain Council, the British Association of Psychopharmacology, the British Neuroscience Association, and the European College of Neuropsychopharmacology. He was Chair of the Advisory Committee on the Misuse of Drugs, and founded DrugScience. He has published over 500 research papers, a similar number of reviews/book chapters, 8 government reports and 36 books. Professor Susumu Higuchi, MD, PhD is Director Emeritus of the National Hospital Organization Kurihama Medical and Addiction Center, and Director of the WHO Collaborating Centre for Research and Training on Substance Use and Addictive Behaviours. He has been involved in many domestic and international scientific activities, including serving as President of the International Society for Biomedical Research on Alcoholism and the Japanese Society of Alcohol-Related Problems. Dr. Higuchi has written more than 300 peer-reviewed scientific papers, published in established international books and journals, and more than 700 papers in domestic books and journals. For several decades Dr. Higuchi has worked on alcohol and gambling policy and programs, and has served as chair or committee member on many Japanese governmental initiatives. He has also closely collaborated with WHO in the field of disorders due to substance use and addictive behaviours. Professor Sawitri Assanangkornchai, MD, PhD, FRCPsychT is Professor of Psychiatry in the Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand. She is also the Director of Centre for Alcohol Studies, a national granting agency under the support of the Thai Health Promotion Foundation, with a mission to promote research and policy development on alcohol control. Dr. Assanangkornchai's research interests include epidemiological and clinical studies on alcohol- and substance-related problems, behavioural addiction and mental health problems. Dr. Assanangkornchai is currently the President of the Asia Pacific Society for Alcohol and Addiction Research (APSAAR). She was a member of the Workgroup on the Classification of Substance-Related and Addictive Disorders for the ICD-11 Mental and Behavioural Disorders and the Technical Expert Group on Alcohol and Drug Epidemiology of the WHO. She has published ten books and over 130 scientific papers, reviews, and book chapters. Professor Henrietta Bowden-Jones OBE, FRCPsych, BA(Hons), DOccMed, MD is a Consultant Psychiatrist in Addictions in the UK and Director of the National Problem Gambling Clinic, and Founder and Director of the National Centre for Gaming Disorders. She was appointed Officer of the Most Excellent Order of the British Empire (OBE) in 2019, for service to addiction treatment and research. As a neuroscience researcher, she is Honorary Professor, Faculty of Brain Sciences, University College, London, and Senior Visiting Research Fellow in the Department of Psychiatry, University of Cambridge. She is Vice-President of the Royal Society of Medicine for 2022-2025, Past President, of the Medical Women's Federation, In 2020 she was honoured with the Royal College of Psychiatrists' Psychiatrist of the Year award. She is a member of the WHO Workgroup on Gaming Disorders. She is an advisor to the UK Government on matters pertaining to gambling disorder, gaming disorder and mental health. Professor Wim van den Brink, MD, PhD receiv