Dan Furmedge MBBS MSc FRCP DLM DRCOG RCPathM FHEA AKC, Consultant Physician in Geriatric & Internal Medicine, Guy's and St Thomas' NHS Foundation?Trust; and Honorary Senior Clinical Lecturer, Kings College London London, UK Rudy Sinharay MBChB MRCP(UK) MD(Res), Consultant Physician in Respiratory & General Internal Medicine, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK