Nutraceutical Delivery Systems Promising Strategies for Overcoming Delivery Challenges

This book highlights recent innovative work in nutraceutical delivery systems, focusing on strategies and approaches for delivering maximum health benefits from foods. It presents recent research-oriented work from diverse global perspectives on isolation techniques for nutraceutical components, phytosomes, liposomes, solid dispersions, micelles, self-emulsifying drug delivery systems, microemulsions, solid lipid nanoparticles, polyelectrolyte complexes, oral delivery, polymeric nanoparticles, and more. The book begins with an overview of recent facts and diverse perspectives on the use of nutraceuticals in medicine and proceeds to discuss recent techniques in isolation of nutraceuticals from plants and in solubility enhancement. It looks at innovations and advances in nanoparticles-based nutraceutical delivery, such as in solid lipid nanoparticles (SLNs), fabrication methods of therapeutic nanoparticles, and polymeric nanoparticles-based nutraceutical delivery system. It also discusses vesicular delivery systems and biphasic systems for nutraceutical applications. The book also looks at the challenges in oral delivery and the latest taste-masking techniques.

PART 1: Basics Concepts and Global Progress in Nutraceutical Sciences 1. Recent Facts and Global Perspectives of Nutraceuticals in Medicine Manisha Puranik, Jyotiranjan Roul, and Pramod Yeole 2. Recent Techniques in Isolation of Nutraceuticals from Plants Sumit Arora, Shobha Ubgade, and Alok Ubgade PART 2: Advances in Nanoparticles-Based Nutraceutical Delivery 3. Solid Lipid Nanoparticles (SLNs): An Emerging Platform for Nutraceutical Delivery Vishal C. Gurumukhi, Sanjaykumar B. Bari, and Kaushalendra Chaturvedi 4. Fabrication Methods of Therapeutic Nanoparticles: Potential Opportunities and Challenges in Drug Delivery and Nutraceutical Delivery Swapnil G. Patil, Surendra G. Gattani, Kiran Patil, Shashikant Bagade, and Debarshi Kar Mahapatra 5. Polymeric Nanoparticles-Based Nutraceutical Delivery System Mahesh P. More, Prashant K. Deshmukh, Prajakta Joshi, and Prasad A. Pofali PART 3: Advances in Vesicular Delivery Systems for Nutraceutical Applications 6. Phytosomes and Phytosomal Nanoparticles: A Promising Drug Delivery System for Flavonoids and Nutraceuticals Darshan R. Telange, Shirish P. Jain, Anil M. Pethe, and Vivek S. Dave 7. Liposomal Delivery System for the Effective Delivery of Nutraceuticals and Functional Foods Pranesh Kumar, Debarshi Kar Mahapatra, Dileep Kumar, Mohamad Taleuzzmann, Sachin Borikar, Vishal S. Gulecha, Amar G. Zalte, Kanhaiya M. Dadure, Manisha Puranik, Manik Das, and Tomy Muringayil Joseph PART 4: Biphasic Systems for Delivering Nutraceutical Products 8. Self-Emulsifying Drug Delivery System for Potential Nutraceuticals: Solidification Techniques and Quality by Design (QbD) Shailesh S. Chalikwar, Pankaj V. Dangre, Poorva P. Dusad, and Sanjay J. Surana 9. Microemulsions for Improvement in Bioavailability of Potential Nutraceuticals Vaishali Kilor, Nidhi Sapkal, Shobha Ubgade, and Abhay Ittadwar PART 5: Advanced Innovative Nutraceutical Delivery Systems 10. Challenges in Oral Delivery of Nutraceuticals: From Formulation Scale-Up to Clinical Assessment Kaushalendra Chaturvedi, Harsh Shah, and Bhavin Gajera 11. Solid Dispersion Techniques for Improvement of Dissolution and Bioavailability of Nutraceuticals Abhijeet D. Kulkarni, Unnati M. Patel, Pallavi S. Kandalkar, Ankita A. Gorhe, Anjali S. Sabale, Asmita K. Kedar, Snehal S. Jagtap, and Vaibhav A. Mahale 12. Potential Applications of Polyelectrolyte Complexes in Pharmaceutical and Nutraceutical Delivery Chandrakantsing V. Pardeshi, Debarshi Kar Mahapatra, Veena S. Belgamwar, and Sanjay J. Surana Part 6: Miscellaneous Nutraceutical Delivery Systems 13. Micelles: An Insight for Nutraceuticals and Regulatory Status Pankaj Padmakar Nerkar 14. Insights into the Latest Taste Masking Techniques for Nutraceutical Products and Functional Foods Parag A. Kulkarni, Amit B. Page, and Debarshi Kar Mahapatra

Pankaj V. Dangre, PhD, is Associate Professor and Vice-Dean (Research), Department of Pharmaceutics, Datta Meghe College of Pharmacy, Maharashtra, India. He was formerly Assistant Professor in the Department of Pharmaceutics at the R. C. Patel Institute of Pharmaceutical Education and Research at North Maharashtra University, Nagpur, India. He taught modern pharmaceutics and novel drug delivery systems at undergraduate and postgraduate levels and has mentored students in research projects. His interests include drug delivery, formulation development, and nutraceutical innovations. He has published research papers on bioavailability enhancement and controlled-release formulations along with book chapters and laboratory manuals on basic pharmaceutical formulations and physical pharmaceutics. Debarshi Kar Mahapatra, PhD, is Assistant Professor in the Department of Pharmaceutical Chemistry at Dadasaheb Balpande College of Pharmacy at RTM Nagpur University, Nagpur, India. He has taught medicinal chemistry and computational chemistry at both undergraduate and postgraduate levels and has mentored students in research projects. He has published research papers, review articles, and imperative case studies in various reputed international journals and has presented his original contributions at several international platforms, for which he received several awards by scientific and professional bodies. He has contributed to edited books, syllabus-based textbooks, lab manuals, book chapters, magazine articles, and guidebooks on pharmaceutical chemistry, natural products, pharmacology, and pharmaceutics. Presently, he is as an active reviewer and serves as an editorial board member for several journals of national and international repute. He is an active member of a number of professional and international scientific societies.