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gupta madhu (curatore); chauhan durgesh nandini (curatore); sharma vikas (curatore); singh chauhan nagendra (curatore) - novel drug delivery systems for phytoconstituents

Novel Drug Delivery Systems for Phytoconstituents

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Dettagli

Genere:Libro
Lingua: Inglese
Editore:

CRC Press

Pubblicazione: 08/2019
Edizione: 1° edizione





Note Editore

Novel Drug Delivery Systems for Phytoconstituents discusses general principles of drug targeting, construction material and technological concerns of different phytoconstituent in delivery systems. It focuses on the development of novel herbal formulations and summarizes their method of preparation, type of active ingredients, route of administration, biological activity and their applications. It dicusses therapeutic activities of plant derived chemicals, their limitations in clinical applications and novel drug delivery solutions to overcome them to provide better therapeutic effects with controlled and targeted drug delivery. Focus on drug delivery of phytomolecules Act as bridge between natural product scientist and clinical doctors Discusses mechanism of poor bioavailability of herbal molecules Increases awareness towards phytochemical efficacy Summarizes efficient novel delivery systems-based formulations. It extensively covers the applications of novel drug delivery systems including polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid capsules, liposomes, phytosomes, microsphere, transferosomes, and ethosomes. Some chapters are especially focused on anticancer phytodrugs, silymarin, andrographolide, berberine, and curcumin delivery with special emphasis on their application.




Sommario

Contents Preface ..................................................................................................................................................... vii Editors ....................................................................................................................................................... ix Contributors .............................................................................................................................................. xi Section I Drug Delivery Systems 1. Novel Drug Delivery Systems for Phytoconstituents: Current and Future Prospects .............. 3 Vikas Sharma, Madhu Gupta, Durgesh Nandini Chauhan, Nagendra Singh Chauhan, Ramesh K.Goyal, and Kamal Shah 2. Nanocarriers Systems and Their Application for the Delivery of Different Phytoconstituents ........................................................................................................................... 9 Ebru Altuntas, Gülgün Yener, and Burcu Özkan 3. Liposome-Based Nanocarrier System for Phytoconstituents .................................................... 45 Ngoc Thuy Trang Le, Linh Phuong Tran Pham, Diem Huong Tran Nguyen, Ngoc Hoang Le, Tuong Vi Tran, Cuu Khoa Nguyen, and Dai Hai Nguyen 4. Phytosomes as Novel Carriers of Herbal Extracts ...................................................................... 69 Sevgi Güngör, Özlem Akbal-Dagistan, Evren Algin Yapar, Murat Kartal, and Yildiz Özsoy 5. Lipid-Based Nanoparticles: SLN, NLC, and MAD .................................................................... 81 Rita Cortesi, Paolo Mariani, Markus Drechsler, and Elisabetta Esposito Section II Application of Phytodrug Delivery 6. Phytosomes as Useful Drug Delivery Systems for Cosmeceutical Application ...................... 105 Francesca Froiio, Agnese Gagliardi, Massimo Fresta, Donato Cosco, and Donatella Paolino 7. Novel UV Filtering Agents for Next-Generation Cosmetics: From Phytochemicals to Inorganic Nanomaterials ..............................................................................................................121 Aditya Arya and Jayanti Jha 8. Development of Ethosome Formulation for Topical Therapeutic Applications ..................... 137 Mansoureh Nazari Vishkaei, Mohamed B. Khadeer Ahamed, and Amin Malik Shah Abdul Majid 9. Application of Phytodrug Delivery in Anticancer Therapy ..................................................... 157 Xiuhua Wang and Shirui Mao Section III Phytomolecule Drug Delivery 10. Improved Silymarin Characteristics for Clinical Applications by Novel Drug Delivery Systems ........................................................................................................................... 195 Maryam Tabarzad, Fatemeh Ghorbani-Bidkorbeh, and Tahereh Hosseinabadi 11. Silymarin—A Scintillating Phytoantioxidant: Clinical Applications and Bio-delivery Problems ........................................................................................................................................ 223 Aditya Arya, Subhojit Paul, and Anamika Gangwar 12. Innovative Delivery Systems for Andrographolide Delivery ................................................... 241 A. C. Santos, J. A. D. Sequeira, F. Veiga, A. Figueiras, and A. J. Ribeiro 13. Polymeric Colloidal Carriers for Natural Polyphenolic Compounds ......................................261 Maria Rosaria Lauro, Teresa Musumeci, Francesca Sansone, Giovanni Puglisi, and Rosario Pignatello 14. Drug Delivery Systems for the Controlled Delivery of Berberine ........................................... 283 Rosario Pignatello, Simona Cianciolo, and Agata K. Giuffrida 15. Lipid-Based Nanoformulations from Plants for Sustainable Drug Delivery ......................... 301 Ilaria Clemente, Ilaria Colzi, and Sara Falsini 16. Nanotechnological-Based Drug Delivery System for Magical Molecule Curcumin: Delivery, Possibilities and Challenges .........................................................................................313 Madhu Gupta, Vikas Sharma, Durgesh Nandini Chauhan, Nagendra Singh Chauhan, Kamal Shah, and Ramesh K. Goyal Index .......................................................................................................................................................333




Autore

Editors Madhu Gupta has research experience pertaining to drug delivery to nanoformulations for magical molecule delivery, bioligands for targeting of bioactives and drug moiety, biopolymers, cancer nanomedicine, as well as topical delivery that is carried out at the Department of Pharmaceutical Sciences, Dr. H.S. Gour Central University, Sagar. Dr. Gupta has done her B. Pharm (Gold Medalist), M. Pharm, PhD in Pharmaceutics with experience of more than 12 years in academics, administrative functions, and research in areas of pharmaceutical nanotechnology and targeted drug delivery related to cancer, fungal infection, and psoriasis. Presently she is working as an officer on special duty to Vice- Chancellor in Delhi Pharmaceutical Sciences and Research University. Along with teaching and research, she is Chief Operating Officer of World Class Skill Centre courses, PRO, website In-charge, IQAC in addition to much other managerial work. She is pioneer scientist in the fields of nanotechnology and drug delivery. She has judiciously exploited bioligands for targeting of bioactives and drug moiety. She has over 40 research publications to her credit published in journals of high scientific impact and contributed 18 chapters in various renowned books and to several international and national books. Dr. Gupta has H-index of 12, i10-index of 14, and more than 600 citations. She has been awarded by various national and international conferences in the form of best oral and poster presentation award and other national and international awards. She has supervised 15 MPharm students. Dr. Gupta has availed several prestigious fellowships and awards SRF AICTE (NDF), JRF (AICTE), Travel grant awards (DST, ICMR, INSA, and DBT, MPCST), Prof. G.P. Nair Award (2004), and Prof. C.S. Chauhan Award (2004). She has her research work at BioAsia Innovation Award—2012, Grace India Awards, Youth Education Award 2018, and Young Researcher Award. She has successfully completed one project that is funded by MPCST Bhopal. She is the nominee of CPCSEA and also an active member of various pharmaceutical bodies such as APTI and others. She is a reviewer of various journals of repute. She has attended various conferences/ seminars/workshops/FDPs as organizer/coordinator/resource person/participant. Dr. Gupta and her team have been selected for funding of one start-up. Durgesh Nandini Chauhan completed her BPharm degree in Pharmacy from the Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, India, and her MPharma (pharmaceutical sciences) in pharmaceutics from Uttar Pradesh Technical University, currently Dr. A.P.J. Abdul Kalam Technical University, Lucknow, in 2006. Mrs. Durgesh Nandini Chauhan has 10 years of academic (teaching) experience from Institutes of India in pharmaceutical sciences. She taught such subjects as pharmaceutics, pharmacognosy, traditional concepts of medicinal plants, drug-delivery phytochemistry, cosmetic technology, pharmaceutical engineering, pharmaceutical packaging, quality assurance, dosage form designing, and anatomy and physiology. She is member of the Association of Pharmaceutical Teachers of India, SILAE: Società Italo-Latinoamericana di Etnomedicina (The Scientific Network on Ethnomedicine, Italy), and so forth. Her previous research work includes Penetration Enhancement Studies on Organogel of Oxytetracycline HCL. She also attended AICTE-sponsored Staff Development Program on “Effects of Teaching and Learning Skills in Pharmacy-Tool for Improvement of Young Pharmacy Teachers” and workshop on Analytical Instruments. She has written more than 10 publications in national and international journals, 13 book chapters, and authored 2 books: Optimization and Evaluation of an Organogel and Plant and Marine Based Phytochemicals for Human Health: Attributes, Potential, and Use. She is also active as a reviewer for several international scientific journals and active participant in national and international conferences such as Bhartiya Vigyan Sammelan and International Convention of Society of Pharmacognosy. Presently she is part of the Ishita Research Organization, Raipur, India, as a freelance writer and guiding pharmacy, Ayurvedic, and science students in their research projects. Vikas Sharma is Associate Professor and Principal Shri Rawatpura Sarkar Institute of Pharmacy Datia, India. Dr. Sharma obtained his BPharm from Jiwaji University Gwalior, MPharm in Pharmacognosy, and PhD from Dr. H.S. Gour Central University Sagar, India. Dr. Sharma has more than 12 years of teaching and research experience. He has made significant contributions in the area of medicinal plant research. He has been working on evidence-based validation of medicinal plants and pharmacological screening of herbal drugs. Dr. Sharma works on marker and biomarker analysis of herbs for quality evaluation. He has also made significant contributions to development of chemical profiling of extracts and formulation through TLC, HPTLC, and LC-MS. He is










Altre Informazioni

ISBN:

9781138481374

Condizione: Nuovo
Dimensioni: 10 x 7 in Ø 1.83 lb
Formato: Copertina rigida
Illustration Notes:20 tables, 18 halftones and 56 line drawings
Pagine Arabe: 350


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