Natural Product Experiments in Drug Discovery

This detailed volume explores a wide range of evidence-based complementary medicine and various bio-analytical techniques used to define botanical products. Collecting recent work and current developments in the field of contemporary phytomedicine as well as their future possibilities in human health care, the book includes unique contributions in the form of chapters on phytomedicine and screening biological activities explained with diverse hyphenated techniques, as well as issues related to herbal medications, such as efficacy, adulteration, safety, toxicity, regulations, and drug delivery. Written for the Springer Protocols Handbooks series, chapters feature advice from experts on how to best conduct future experiments. 

Phytochemical, Antioxidant, and Flavonoid Investigation of Methanolic Leaf Extract of Piliostigma Thoningii (Schum.).- A Comparative Evaluation of Organoleptic, Physicochemical, Proximate, and Mineral Composition of Syzygium laetum and Syzygium occidentale, Endemic to Western Ghats: A Search for Low-Cost Nutraceuticals.- Chemical Characterization, Biological Activities, and Some Medicinal Uses of Different Sweet Basil (Ocimum basilicum L.) Genotypes.- Estimation of Primary, Secondary Metabolites, and In Vitro Free Radical Scavenging Activities with Ficus tsjahela Burm. F. Crude Extracts.- Evaluating the Lipid Profile and Mineral Composition of the Seed Oil of Caesalpinia sappan L. (Caesalpiniaceae).- Phytochemical Screening, Physicochemical Analysis, and Powder Characterization of Selected Litsea Species Endemic to the Southern Western Ghats.- Metabolite Profiling of Bioactive Compounds in Selected Species of Gomphostemma Wall. ex Benth.from the Western Ghats by GC-MS Analysis.- Phytochemistry and Pharmacology of Aromatic Medicinal Plant Commiphora caudata(Wight &Arn.)Engl..- Unravelling the Phytochemistry of Ethnomedicinal Tree Pajanelia longifolia (Wild.) K. Schum..- Comparative Phycochemical Investigation and Antioxidant Content of Two Marine Seaweeds.- Evaluation of Nutritional, Antioxidant and Anti-Arthritic Activity of Hedychium coronarium J. Koenig Rhizome.- Phytochemical, Pharmacognostic, and In Vitro Acetylcholinesterase Inhibitory Activities of Cipadesa baccifera Leaves.- Comparative Study of Drug Efficiency of Scemecarpus anacardium and Tridax procumbens against Zika Virus.- Evaluation of In Vitro Antioxidant Activity of Oldenlandia dineshii: An Endemic Plant from the Hillocks of Palakkad District, Kerala, India.- Identification of Secondary Metabolites through HR-GC-MS: Antibacterial and Antifungal Activity from Root Fractions of Alstonia scholaris (L.) RBr. from Andhra Pradesh, South India.- In Vitro Models on Inhibition of Inflammatory Mediators by Ethanolic Extract of Careya arborea Roxb. Bark in Lipopolysaccharide-Induced RAW 264.7 Cell Lines.- Pharmacological Elucidation of Antioxidant, Hypoglycemic, and Anti-Inflammatory Potentials of Phyllanthus candolleanus (Wights ARN) Chakrab..- a-Glucosidase Inhibition and Upregulation of PPAR? by Flavonoid Naringenin from Tinospora sinensis Stem, a Possible Mechanism of Antidiabetic Activity.- Purification and Characterization of a Cysteine Protease from Sprouted Lablab purpureus Seed Radicle Extract: Its Effect on Blood Coagulation.- Effect of Sterilization Agents, Growth Regulators, and Activated Charcoal on Callus Cultures of Evolvulus alsinoides (Linn.) Linn.- Bryophytes: A Myriad Hue of Bio-Resources with Therapeutic Potentialities.- Recent Biotechnological Approaches for the Enhancement of Artemisinin Production from Cell Culture System of Artemisia annua L: Medicinal Plant with Potent Anti-Malarial Properties.- The Utility of Natural Mucilage from the Medicinal Plant, ‘Patha’ (Cyclea peltata), as an Alternative for Solidifying Agent in Cell Growth Media.- Microwave Irradiation-Assisted Extraction and Synthesis of Silver Nanoparticles Using Tree Tomato Fruit Pulp (Solanum betaceum Sendt.) and Determination of In Vitro Cytotoxic Effect on MCF-7 Cells.- Characterization of Crystals Isolated from the Caesalpinia sappan Seeds: A Comparative In Silico Analysis on Bioactivity of Sappan Diterpenoids.- Computational Analysis of Natural Compounds as Potential Isocitrate Dehydrogenase 1 Inhibitor for the Treatment of Ovarian Cancer.- Drug Efficiency of Oroxylum Indicum and Taxus Wallichiana Against Colon-Associated Diseases: In Silico Studies.- Gas Chromatography-Mass Spectrometry Analysis of Phytoconstituents from Garcinia gummi-gutta Seed Extract: Trypsin Inhibition Study of Extract and Molecular Docking Study.- In Silico Analysis of Anti-Inflammatory Activity of Quercetin from M. Calabura Fruit.- Phytochemical Investigation, Molecular Docking Studies, and Biological Efficacy of Rhizome Essential Oil Composition of Costus Speciosus.- Ficus talboti King: Anti-Nociceptive and Anti-Inflammatory Properties of Methanol Extract of Stem Bark.- Phytochemical and Antioxidant Analysis of Phellinus adamantinus and P. hohnelli.