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This book gives a complete overview of current developments in the nano drug delivery technology in the management of neurological disorders and brain diseases. The book is divided into three main sub-sections: A) Fundamental study on nanomaterials, nanocarriers, and nanoformulation-based drug delivery in neurological diseases management, B) Nano drug delivery therapy - a novel approach towards common neurological disorders and C) Novel nano delivery strategies in targeted neurological diseases management. This collective work presents diverse nano-based drug delivery technologies that are high-throughput, reliable, pioneering, and applicable to researchers of different countries despite their socio-economic conditions. It hopefully encourages researchers, innovators and policymaker to adapt nanomaterial-based drug delivery vehicles technologies using diverse nano-based formulation techniques as targeted therapy for treating and managing neurological disorders.
Santosh Kumar Rath is a medicinal and natural product chemist with more than 10 years of experience in research, academia, and industry. Rath’s received his doctorate from AcSIR at CSIR-Institute of Minerals and Materials Technology (CSIR-IMMT), Bhubaneswar, India. Presently he is working as Assistant Professor in Pharmaceutical Chemistry at the Department of SoPPHI, Faculty of Pharmacy, DIT University, Dehradun, Uttarakhand, India. Formerly, he worked as an Associate Professor and Research Head at the Department of Pharmaceutical Chemistry, Danteshwari College of Pharmacy, Jagdalpur, Chhattisgarh, India (2020-2022). He also worked as Research Associate (CSIR-RA) in the School of Chemistry & Biochemistry at Thapar Institute of Engineering & Technology, Patiala, India (2018-2020). He received Research Associateship from CSIR in 2018 and Senior Research Fellowship (ICMR-SRF) from ICMR, New Delhi India in 2013. He did research at the CSIR-Indian Institute of Integrative Medicine(CSIR-IIIM), Jammu, India. He has many publications to his credit, published more than 27 research papers in highly reputed international journals, as well as 4 book chapters two edited books, and 1 Indian patent. His area of research is Natural Product Chemistry and Organic Synthesis, in which he is expertise in the isolation, identification, and characterization of bioactive secondary metabolites, and structural modification of major chemical constituents from plants as well as fungal sources. He is acquainted with various chromatographic techniques such as column, Preparative TLC, and HPLC for separating and purifying compounds. He is well aware of the interpretation of spectroscopic data viz., 1D and 2DNMR, MASS, IR, etc. His research involves multistep synthesis of biologically active synthetic and/or natural product-based hybrid scaffolds for lead identification in special targets for neurological disease, cancer, HIV, Covid-19, and infectious diseases. His research mainly focuses on synthesizing novel P-gp and bacterial efflux pump inhibitors, besides synthetic modifications of the bioactive natural products for better activity/minimize toxicity profiles. Currently, he is developing new synthetic methodologies for the C-H functionalization of heterocycles and other medicinally relevant molecules. He contributed substantially to many research projects and is also having collaborative research work with many other research groups.
Vagish Dwibedi did his B.Sc from Lucknow University, Lucknow, Uttar Pradesh, and Ph.D. from Thapar Institute of Engineering and Technology, Patiala, India. Dwibedi is an academician and researcher with more than 8 years of experience in biotech research and development. He has carried out research projects and consultancy work in the areas of plant-microbe interaction/ bioassay-guided drug-discovery and development, food security/sustainable agriculture and waste water treatment. Presently he is working as Assistant Professor at University Institute of Biotechnology, Chandigarh University, Gharuan Mohali, Punjab. Formerly, he was worked as Research Scientist at Agpharm Bioinnovations LLP incubated at Thapar Institute of Engineering & Technology, Patiala, India. He was also Winner in Down select competition- DST- Lockheed Martin- Tata Trust _IIGP 2.0 (2k18) (India Innovation Growth Programme 2.0) Innovation ID: IIGPUIBSUNB (The award carries financial support up to 25 Lac INR.). He work is directed towards the development of screening platforms for different biological activities such as anti-microbial, anti-oxidant, anti-cancer, or finding novel molecules that interfere in the mechanism of development of diseases such as Alzheimer Dementia (AD), Parkinson disease (PD), Obesity, Anti-gout (arthritis) and type 2 diabetes. He is also interested in food security, which predominantly involves the exploitation of plant-microbe interaction to combat abiotic stress and post-harvest preservation to enhance the shelf life of fresh crop/horticulture produces. He has published more than 25 research papers in various national and international journals and published 2 Indian patent.
Azamal Husen is presently working as a Professor at Sankalchand Patel University, Visnagar, India; and Adjunct Professor at Graphic Era (Deemed to be University), Dehradun, Uttarakhand, India. He is also working as an Invited Professor at University Putra Malaysia, Selangor, Malaysia. Previously, he served as Professor and Head of the Department of Biology, University of Gondar, Ethiopia; and worked as a Foreign Delegate at Wolaita Sodo University, Wolaita, Ethiopia. He also worked as a Visiting Faculty of the Forest Research Institute and the Doon College of Agriculture and Forest at Dehra Dun, India. His research and teaching experience of 25 years encompasses biogenic nanomaterial fabrication and application; plant responses to nanomaterials; plant adaptation to harsh environmen
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