Lung Transplantation Principles and Practice

Lung Transplantation: Principles and Practice covers the current practice in donor and recipient management as well as current treatment strategies and outcomes. With 39 chapters from international experts in the field, the book is divided into four broad sections: General Topics, Donor Management, Recipient Management and Outcome, and the Future of Lung Transplantation. The book discusses significant advances achieved in the past decade in areas such as donor allocation, organ preservation and management, recipient selection, management and support, surgical and critical care techniques, immune suppression, and infection prophylaxis. Specific instances of pulmonary disease that commonly necessitate lung transplantation are also covered. Generously illustrated in full color, this valuable resource is relevant to both specialists and other providers who may refer or care for patients before and after transplantation.

GENERAL TOPICS. History of Lung Transplantation. Immunology of Lung Transplantation. Ethical Considerations in Transplantation: A Focus on Lung Transplantation. Indications for Lung Transplantation and Patient Selection. Recipient Management before Transplantation. DONOR MANAGEMENT. Allocation of Donor Lungs. Donor Selection and Management. Non-Heart-Beating Donors. Donor Lung Preservation. Donor Procurement. Ex Vivo Lung Perfusion. RECIPIENT MANAGEMENT AND OUTCOME. The Humoral Response to Lung Transplantation. Anesthesia for Lung Transplantation. Mechanical Ventilation and Extracorporeal Membrane Oxygenation (ECMO) Bridges to Lung Transplantation. Single-Lung Transplantation: Technical Aspects. Bilateral Sequential Lung Transplantation: Technical Aspects. Heart-Lung Transplantation: Technical Aspects. Lobar Lung Transplantation from Living Donors: Technical Aspects. Technical Aspects of Redo Lung Transplantation and Lung Transplantation after Previous Thoracotomy. Lung Transplantation for Idiopathic Pulmonary Fibrosis. Lung Transplantation for Emphysema and a1-antitrypsin Deficiency. Lung Transplantation for Cystic Fibrosis and Bronchiectasis. Lung Transplantation for Pulmonary Hypertension. Lung Transplantation for Connective Tissue Disorders. Posttransplantation Critical Care Management. Primary Graft Dysfunction. Management of Surgical Complications. Immunosuppression Strategies in Lung Transplantation. Viral Infections in Lung Transplantation. Fungal Infections in Lung Transplantation. Bacterial Infections after Lung Transplantation. Diagnosis of Lung Rejection and Infection: A Pathologist’s Perspective. Obliterative Bronchiolitis/Bronchiolitis Obliterans Syndrome: Etiology, Diagnosis, and Management. Chronic Lung Allograft Dysfunction Other Than Bronchiolitis Obliterans Syndrome. Medical Complications of Lung Transplantation. Malignancy Following Lung Transplantation. Quality of Life Following Lung Transplantation. FUTURE OF LUNG TRANSPLANTATION. Future Therapies in Lung Transplantation. New Horizons in Lung Transplantation.

Edited byWickii T. Vigneswaran, MD, MBA, FRCSC, FRCS(CTh), FACS, professor and chief of thoracic surgery, Loyola University Medical Center and Stritch School of Medicine, Chicago (Maywood), Illinois, USAEdward R. Garrity, Jr., MD, MBA, professor of medicine, vice chair of clinical operations, and associate director of transplantation services, University of Chicago, Illinois, USAJohn A. Odell, MBChB, FRCS(Ed), FACS, emeritus professor of surgery, Mayo Clinic, Jacksonville, Florida, USA