Introduction Emilie Cloatre and Martyn Pickersgill, Section 1 Law, Expertise and Public Participation Chapter 1Science, uncertainty and the normative question of epistemic governance Sujatha Raman, Chapter 2 Contingent participation: imaginaries of sustainable technoscientific innovation in the European Union Mark Flear and Thomas Pfister, Chapter 3The voice of silence: UK patients’ silent resistance to the assisted reproduction regulationsIlke Turkmendag, Section 2 Objects and Epistemologies in Criminal Law Chapter 4 Unchaining research: processes of dis/empowerment and the social study of criminal law and investigationBarbara Prainsack, Chapter 5 Making the colposcope "forensic": The medico-legal management of a controversial visualisation device Gethin Rees, Chapter 6 Telling tales: some episodes from the multiple lives of the polygraph machine Andrew Balmer, Section 3 Regulation, Ethics and Values Chapter 7 Through the thicket and across the divide: successfully navigating the regulatory landscape in life sciences research Graeme Laurie and Shawn Harmon, Chapter 8, Misconduct hunting: research integrity via law, science and technology Marie-Andree Jacob, Chapter 9 Financial derivatives and the challenge of performation: where contingency meets contestability Donatella Alessandrini, Section 4 Law, Technoscience and the Stabilization of Knowledge Chapter 10 Epistemic Jurisdictions: Science and Courts in Regulatory (De)centralisation David Winickoff, Chapter 11 Un-knowing exposure: toxic emergency housing, strategic inconclusivity and governance in the US Gulf South Nick Shapiro, Chapter 12 A likely story: HIV and the definition of disability in UK employment equality law, 1996-2005 Emily Grabham, Chapter 13 Paper prototypes Alain Pottage