Disponibilità: Normalmente disponibile in 15 giorni A causa di problematiche nell'approvvigionamento legate alla Brexit sono possibili ritardi nelle consegne.
Recent research has revealed the importance of immunological mechanisms and inflammation in delaying damage and/or promoting repair after an acute injury to the central nervous system. This book provides a comprehensive and up-to-date overview of the role of immunological mechanisms and therapies for treating acute neurological injuries such as cerebral ischemia, hemorrhage, and brain and spinal cord trauma. In several sections, the contributing authors provide a review of immunological mechanisms involved in neurological injury and of various translational and clinical research aimed at harnessing those mechanisms for better patient outcomes.
Sommario
Old dogmas, surprising complexities, and novel therapeutic targets.- The critical roles of immune cells in acute brain injuries.- Vascular Inflammation in Ischemic Stroke: Adhesion Receptors Controlling Leukocyte-Endothelial Interactions.- Immune Cell-Derived Free Radicals in Acute Brain Injury.- The complement cascade in acute brain injury.- Matrix Metalloproteinases as an Inflammatory Mediator in the Neurovascular Unit.- Toll-Like Receptors in Ischemic Stroke and other Acute Brain Injuries.- Ion Transporters in Microglial Function: New therapeutic targets for neuroinflammation in ischemic stroke?.- Inflammation After Acute Brain Injuries Affects the Developing Brain Differently than the Adult Brain.- Systemic Immune Responses after Experimental Stroke.- Infectious Burden and Risk of Stroke.- Inflammatory Biomarkers in Patients with Acute Brain Injuries.- In vivo Imaging of Neuroinflammation in Acute Brain Injury.- Inflammation as a therapeutic target after subarachnoid hemorrhage:advances and challenges.- Minocycline, a Tetracycline Derivative, as a Potential Protective Agent for Acute Stroke.- Tolerization to Brain and Vascular Antigens: Targeting Autoimmunity after Acute Brain Injuries and Preventing Stroke.- The Role of PPARg in Stroke.- CD36: an inflammatory mediator in acute brain injury.- Cool Down the Inflammation: Hypothermia as a Therapeutic Strategy for Acute Brain Injuries.- Index.
Altre Informazioni
ISBN:
9781461489146
Condizione: Nuovo
Collana: Springer Series in Translational Stroke Research
Dimensioni: 235 x 155 mm
Formato: Copertina rigida
Illustration Notes:X, 386 p. 34 illus., 21 illus. in color.
Pagine Arabe: 386
Pagine Romane: x
Dicono di noi
Per noi la tua privacy è importante
Il sito utilizza cookie ed altri strumenti di tracciamento che raccolgono informazioni dal dispositivo dell’utente. Oltre ai cookie tecnici ed analitici aggregati, strettamente necessari per il funzionamento di questo sito web, previo consenso dell’utente possono essere installati cookie di profilazione e marketing e cookie dei social media. Cliccando su “Accetto tutti i cookie” saranno attivate tutte le categorie di cookie. Per accettare solo deterninate categorie di cookie, cliccare invece su “Impostazioni cookie”. Chiudendo il banner o continuando a navigare saranno installati solo cookie tecnici. Per maggiori dettagli, consultare la Cookie Policy.
