Handbook of Optofluidics

Optofluidics is an emerging field that involves the use of fluids to modify optical properties and the use of optical devices to detect flowing media. Ultimately, its value is highly dependent on the successful integration of photonic integrated circuits with microfluidic or nanofluidic systems. Handbook of Optofluidics provides a snapshot of the state of the field, captures current trends, and gives insight into the technology of tomorrow, which will enable researchers to tackle challenges and opportunities that it can uniquely answer. Divided into three sections, this comprehensive resource begins by introducing the scientific foundations that contribute to optofluidics. It details the connections to related research areas and reveals the scientific influences currently shaping the design and function of optofluidic systems. It provides brief reviews of those established fields from which optofluidics has evolved, putting special emphasis on how they currently intersect. This introductory material provides a basis for understanding the chapters that follow. The second section explores the synthesis of fundamental concepts to create novel devices, specifically those with optical properties that are manipulated by fluids. A main theme that runs through this part is the dynamic reconfigurability made possible by flowing and reshaping fluids. The final section looks to future applications of the field, presenting recent developments in particle detection and manipulation primarily being developed for biosensing and biomedical applications. Enhanced by thematic connections throughout the chapters that help define the field, this volume is a concise reference for the growing optofluidics community and is poised to provide a stepping stone for continued research in an area that holds promise for a myriad of applications.

Foundations of OptofluidicsIntroduction to Microfluidic and Optofluidic Transport; Mekala Krishnan and David EricksonMicrofabrication; Aaron R. Hawkins, Matthew R. Holmes, Tao Shang, and Yue ZhaoPassive Integrated Optics; Siegfried JanzPhotonic Crystal Hollow Waveguides; Fetah Benabid and P. John RobertsOptoelectronics; Romeo Bernini and Luigi ZeniSpectroscopic Methods; Jin Z. ZhangLab-on-a-Chip; Su Eun Chung, Wook Park, Seung Ah Lee, Sung Eun Choi, Jisung Jang, Sung Hoon Lee, and Sunghoon KwonOptical Elements and DevicesFluid-Controlled Optical Elements; Christian Karnutsch and Benjamin J. EggletonOptofluidic Imaging Elements; Xiaole Mao, Zackary S. Stratton, and Tony Jun HuangOptofluidic Switches and Sensors; Steve Zamek, Boris Slutsky, Lin Pang, Uriel Levy, and Yeshaiahu FainmanOptofluidic Ring Resonators; Jonathan D. Suter and Xudong FanOptofluidic Light Sources; Anders Kristensen and N. Asger MortensenBioanalysisSingle-Molecule Detection; Benjamin Cipriany and Harold CraigheadOptical Trapping and Manipulation; Eric Pei-Yu ChiouFluid-Filled Optical Fibers; Michael Barth, Hartmut Bartelt, and Oliver BensonIntegrated Optofluidic Waveguides; Holger SchmidtRaman Detection in Microchips and Microchannels; Melodie Benford, Gerard L. Coté, Jun Kameoka, and Miao WangPlasmonics; David Sinton, Alexandre G. Brolo, and Reuven GordonFlow Cytometry and Fluorescence-Activated Cell Sorting; Chun-Hao Chen, Jessica Godin, Sung Hwan Cho, Frank Tsai, Wen Qiao, and Yu-Hwa LoAppendix A: Optical Properties of WaterAppendix B: Refractive Index of Liquids and SolidsAppendix C: Viscosity and Surface Tension of Typical LiquidsAppendix D: Common Fluorescent DyesAppendix E: Common Physical ConstantsAppendix F: Common Biological BuffersIndex

Aaron R. Hawkins is an Associate Professor of Electrical and Computer Engineering and the Director of the Integrated Microfabrication Laboratory at Brigham Young University in Provo, Utah. Holger Schmidt is an Associate Professor of Electrical Engineering at the University of California, Santa Cruz.