Handbook of Obesity -- Volume 1 Epidemiology, Etiology, and Physiopathology, Third Edition

In recent years, we’ve developed a much better grasp of the biological and other factors associated with the development of obesity. Reflecting our evolving understanding of causes and consequences, Handbook of Obesity: Epidemiology, Etiology, and Physiopathology provides comprehensive coverage of the biological, behavioral, and environmental determinants of this critical condition. This new edition is divided into five sections exploring essential factors involved in obesity research: History, Definitions, and Prevalence: Changes over time surrounding our notion of obesity, adiposity traits, and the epidemiology of obesity in various populations Biological Determinants of Obesity: Genetic and epigenetic evidence, fetal life and postnatal influences, the use of animal models in research, endocrine issues, molecular aspects, and issues related to viral infection and adiposity Behavioral Determinants of Obesity: The effects of food and ingestive behavior, smoking, breastfeeding, sleep duration, work/leisure time activity, and sedentary behavior Environmental, Social, and Cultural Determinants of Obesity: The role of agriculture and the food industry, the urban environment, social and economic aspects, cultural factors, environmental pollutants, and economic costs Consequences of Obesity: How excess weight affects and exacerbates a range of comorbid conditions, including diabetes, cardiovascular disease, pulmonary disorders, arthritis, and cancer This volume assembles the work of worldwide experts to deliver an up-to-date survey of the most essential information related to the causes of the obesity epidemic.

History, Definitions, and PrevalenceObesity Has Always Been with Us: An Historical Introduction; George A. BrayMeasurement of Total Adiposity, Regional Fat Depots, and Ectopic Fat; Steven B. Heymsfield, Houchun Harry Hu, ZiMian Wang, Wei Shen, and Ye JinAnthropometric Indicators in Relation to the Gold Standards; Peter T. KatzmarzykWorldwide Prevalence of Obesity in Adults; Jacob C. SeidellPrevalence and Consequences of Pediatric Obesity; Nazrat M. Mirza and Jack A. YanovskiObesity in Older Adults in the United States; Tala H.I. Fakhouri, Brian K. Kit, Margaret D. Carroll, Katherine M. Flegal, and Cynthia L. OgdenGender, Ethnic, and Geographic Variation in Adiposity; Timothy Olds and Carol MaherBiological Determinants of ObesityGenetic Component to Obesity: Evidence from Genetic Epidemiology; Louis Pérusse, Treva K. Rice, and Claude BouchardGenes and the Predisposition to Obesity; Marcel den Hoed and Ruth J. F. LoosEpigenetic Mechanisms in Obesity; Robert A. WaterlandFetal and Early Postnatal Life Determinants of Adiposity; Felicia M. Low, Peter D. Gluckman, and Mark A. HansonAnimal Models of Obesity: Perspectives on Evolution of Strategies for Their Development and Analysis of Their Phenotypes; Heike Münzberg, Tara M. Henagan, and Thomas W. GettysAnimal Models of Obesity: Nonhuman Primates; Barbara C. HansenCNS Regulation of Energy Balance; Hans-Rudolf Berthoud and Barry E. LevinGastrointestinal Regulation of Energy Balance; Timo D. Müller, Kristy Heppner, Chun-Xia Yi, Paul T. Pfluger, and Matthias H. TschöpGut Microbiome and Obesity; Patrice D. CaniSympathetic Nervous System and Endocrine Determinants of Energy Balance; Hamid R. Farshchi and Ian A. MacdonaldInsulin Resistance and Obesity; Charmaine S. Tam, Morvarid Kabir, Richard N. Bergman, and Eric RavussinWhite and Brown Adipose Tissue Development; Meghan E. McDonald and Stephen R. FarmerAdipose Tissue Metabolism, Adipokines, and Obesity; Dominique Langin and Max LafontanVisceral Adipose Tissue and Ectopic Fat Deposition; Amalia GastaldelliSkeletal Muscle Metabolism and Obesity; Jeffrey J. Brault, G. Lynis Dohm, and Joseph A. HoumardMitochondrial Bioenergetic Aspects of Obesity and Weight Loss; Mary-Ellen Harper, Robert Dent, and Ruth McPhersonResting Metabolic Rate, Thermic Effect of Food, and Obesity; Yves Schutz and Abdul G. DullooEnergy Cost of Exercise, Postexercise Metabolic Rates, and Obesity; Einat Shalev-Goldman, Trevor O’Neill, and Robert RossEnergy Partitioning, Substrate Oxidation Rates, and Obesity; Angelo Tremblay, Yves Deshaies, and Katherine CianfloneViral Infections and Adiposity; Nikhil V. Dhurandhar, Emily J. Dhurandhar, and Richard L. AtkinsonBehavioral Determinants of ObesityObesity: Influence of the Food Environment on Ingestive Behaviors; Richard D. Mattes and Sze Yen TanObesity and Related Eating Disorders; Brooke A. Bailer, Lauren E. Bradley, and Kelly C. AllisonTobacco Use, Smoking Cessation, and Obesity; Carole Clair, Semira Gonseth, Jacques Cornuz, and Ivan BerlinBreastfeeding and Later Obesity; Nancy F. ButteBeverages and Obesity: Biology, History, Trends; Barry M. Popkin and Frank B. HuSedentary Time and Obesity; Neville Owen and Marc HamiltonOccupational Work and Obesity; Nicholas D. Gilson and Catrine Tudor-LockeLeisure-Time Physical Activity and Obesity; Thrudur Gunnarsdottir, Renee J. Rogers, John M. Jakicic, and James O. HillSustained Short Sleep and Risk of Obesity: Evidence in Children and Adults; Michelle A. Miller, George Smith, Andrew O’Keeffe, and Francesco P. CappuccioEnvironmental, Social, and Cultural Determinants of ObesityRole of Agriculture and the Food Industry in America’s Obesity; James E. TillotsonTransportation Policies and Obesity; David R. Bassett Jr.Urban Environment, Building Design, and Obesity; Reid Ewing and Gail MeakinsSocial and Economic Determinants of Obesity; Lindsay McLarenInfluence of Culture on Obesity; Alison Tovar and Aviva MustBias, Discrimination, and Obesity; Rebecca M. Puhl, Kelly D. Brownell, and Jenny A. DePierre Environmental Chemicals and Obesity; Amanda S. Janesick, Thaddeus T. Schug, Jerrold J. Heindel, and Bruce BlumbergEconomic Costs of Obesity; Ping Zhang, Sundar S. Shrestha, and Rui LiConsequences of ObesityObesity and Mortality Rates; Gary Whitlock and Rachel R. HuxleyObesity and Heart Disease; Peter W.F. WilsonObesity and Hypertension; Raj S. Padwal and Arya M. SharmaObesity and Lipoprotein Metabolism; Sally Chiu and Ronald M. KraussObesity and Type Diabetes; Henna Cederberg and Markku LaaksoObesity and Metabolic Syndrome; Jean-Pierre DesprésObesity and Cancer: Clinical Epidemiology; Andrew G. RenehanInflammatory Causes of Obesity and Metabolic Diseases; Ebru Erbay and Gökhan S. Hotamis¸ligilObesity and Gallbladder Disease; Cynthia W. Ko and Sum P. LeeObesity and Liver: Cell Death, Compensatory Growth, and Repair of Damage; Giovanni TarantinoObesity, Lung Function, and Lung Disease; Nour A. Assad, Jesse H. Alvarado, and Akshay SoodObesity, Arthritis, and Gout; Luke Dawson, Anita E. Wluka, Yuanyuan Wang, and Flavia M. CicuttiniObesity and Mental Health; Lucy F. Faulconbridge and Anthony FabricatoreObesity and Health-Related Quality of Life; Donald A. Williamson and W. Jack RejeskiObesity and Pregnancy Outcomes; Raul Artal and Sarah HopkinsObesity, an Inactive Lifestyle and Low Fitness: The Most Unhealthy Combination; Paul A. McAuley and Steven N. BlairIndex

George A. Bray, MD, MACP, MACE, is a former executive director and current Boyd Professor at Pennington Biomedical Research Center of the Louisiana State University System in Baton Rouge, Louisiana. He is also a professor of medicine at the Louisiana State University Medical Center in New Orleans, an adjunct professor of physiology in the School of Veterinary Medicine, and an adjunct professor of food science in the College of Agriculture at Louisiana State University. His research focuses on physiological mechanisms for obesity and the evaluation of treatment for obesity and diabetes. Claude Bouchard, PhD, is a former executive director and current John W. Barton, Sr. Endowed Chair in Genetics and Nutrition at the Pennington Biomedical Research Center of the Louisiana State University System in Baton Rouge, Louisiana. His research focuses on the genetics of obesity and its comorbidities, as well as on the genetics of adaptation to regular exercise in terms of cardiovascular and diabetes risk factors.