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pavão mauro s.g. (curatore) - glycans in diseases and therapeutics

Glycans in Diseases and Therapeutics




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Dettagli

Genere:Libro
Lingua: Inglese
Pubblicazione: 05/2013
Edizione: 2011





Trama

Initially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions.

This volume of the series “Biology of Extracellular Matrix” reviews the most recent findings on the role of glycans in the development of diseases and the possible therapeutic use of this class of molecules. It shows how the interaction of glycans with growth factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and adhesive proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic stem cell biology. Furthermore, an extensive survey about the structure and pharmacological effects of unique marine glycosaminoglycans is discussed as well as the possibility of using these glycans as therapeutic agents.





Sommario

Heparan Sulfate Proteoglycan in Inflammation and Angiogenesis.- Heparan Sulfate Proteoglycans in Infection.- Glycans in cancer.- Glycosaminoglycans in atherosclerosis and thrombosis.- Glycans in Embryonic Stem Cells.- Heparan sulfate proteoglycans in cancer progression and therapy.- Structure and biological activities of glycosaminoglycan analogs from marine invertebrates: new therapeutic agents?.











Altre Informazioni

ISBN:

9783642267949

Condizione: Nuovo
Collana: Biology of Extracellular Matrix
Dimensioni: 235 x 155 mm
Formato: Brossura
Illustration Notes:XII, 188 p.
Pagine Arabe: 188
Pagine Romane: xii


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