Foundations of Corneal Disease Past, Present and Future

The field of cornea has seen tremendous advances over the last 40 years—this uniquely comprehensive book will discuss the history of these advances, current best practices in important diseases of the cornea and ocular surface, and examine future directions in diagnosis and management. Written by leading experts, many of whom trained under Claes Henrik Dohlman, MD, PhD, whose influence and many invaluable contributions have defined and shaped the field of cornea, each chapter will reflect the state of the art in the various aspects of cornea.

Foundations of Corneal Disease: Past, Present, and Future contains six different sections, opening with an introduction which delves into the evolution of subspecialty training in cornea, and provides a historical perspective of our understanding of ocular surface disease. Section Two addresses perspectives on important corneal and external diseases including infectious keratitis, dry eye, and herpes simplex. Section Three and Section Four address surgery and surgical alternatives, and frontiers in corneal research. Section Six closes this book with a discussion of special topics: imaging the cornea, corneal blindness, eye banking, and clinical trials in dry eye, and explores future directions in this fast-paced field.

Foundations of Corneal Disease: Past, Present, and Future contains is an ideal guide for corneal specialists, ophthalmology residents and fellows planning to enter cornea, corneal scientists, and to those in ophthalmology and visual science interested in a comprehensive resource on cornea and the history of this field.

Foreword - Mark Mannis

Section I. Introduction:

Kathryn Colby – Claes Dohlman’s Contributions to Cornea (with historical photos)

James Aquavella- The Evolution of Subspecialty Training in Cornea

Michael Lemp- Historical Perspective on Our Understanding of Ocular Surface Disease

Peter Laibson- Development of Viral Keratitis Research and Therapy

Section II. Perspectives on Important Corneal and External Diseases:

Eduardo Alfonso – Infectious keratitis

Deborah Pavan Langston – Herpes Simplex

Elisabeth Cohen – Herpes Zoster

Kazuo Tsubota – Dry Eye

Ula Jurkunas and Kathryn Colby – Fuchs dystrophy: Rethinking an Old Disease with Insights from the Laboratory and Clinical Practice

Victor Perez and Reza Dana – Unraveling Corneal Graft Rejection

Haji Saeed - Stevens Johnson Syndrome

Claes Dohlman - Chemical Injuries

C Stephen Foster - Cicatrizing disorders of the ocular surface

Section III. Surgery & Alternatives to Surgery:

Kenneth Kenyon – Advances in Corneal Transplantation

Dimitri T Azar – Striving for Perfect Vision: Insights from Refractive Surgery

Peter Hersh – Collagen Cross-linking for Keratoconus and Corneal Ectasia

Section IV. Frontiers in Corneal Research:

Shigeru Kinoshita – Cultured Cells in the Treatment of Corneal Diseases

Mark Rosenblatt – Understanding Wound Healing in the Cornea

Natalie Afshari – Genetics of Corneal Diseases

Section V. Special Topics:

Sonia Yoo - Imaging the Cornea to Improve Diagnosis and Treatment

Deborah Jacobs – Therapeutic Contact Lenses: An Important Tool in Management of Cornea Disease

Roberto Pineda – Making an Impact on World Corneal Blindness

Oliver Schein – Epidemiology of Corneal Diseases

Shazhad Mian – Eye Banking: History and Future Directions

Jonathan Lass – Insights from Clinical Trials in Corneal Surgery

Gary Foulks – Clinical Trials in Dry Eye: What We Have Learned, What We Still Need to Understand

Section VI. Closing

Reza Dana – Future directions in the field

Kathryn Colby, MD, PhD

Louis Block Professor

Chair, Department of Ophthalmology and Visual Science

The University of Chicago Medicine & Biological Sciences

Chicago, IL

Reza Dana MD, MSc, MPH

Claes H. Dohlman Professor of Ophthalmology

Harvard Medical School 

Director, Cornea & Refractive Surgery, Massachusetts Eye & Ear

Boston, MA