Preface; 1: Martin J Evans: Introduction; 2: Frances A. Brook: Procedures for deriving ES cell lines from the mouse; 3: Yoko Kato and Yukio Tsunoda: Production of ES cell-derived mice; 4: Grant R. MacGregor, Wei Wei Fan, Katrina G. Waymire, and Douglas C. Wallace: Generating animal models of human mitochondrial genetic disease using mouse ES cells; 5: Michael V. Wiles and Gabriele Proetzel: Controlling the differentiation of mouse ES cells in vitro; 6: Yelena S. Tarasova, Daniel R. Riordon, Kirill V. Tarasov and Kenneth R. Boheler: In vitro differentiation of mouse ES cells into muscle cells; 7: Osamu Ohneda and Masayuki Yamamoto: In vitro differentiation of mouse ES cells into haematopoietic cells; 8: Tanja Schmandt, Tamara Glaser and Oliver Br?stle: Lineage selection and transplantation of mouse ES cell-derived neural precursors; 9: Przemyslaw Blyszczuk, Gabriela Kania and Anna M. Wobus: In vitro differentiation of mouse ES cells into pancreatic and hepatic cells; 10: Martin F. Pera, Andrew Laslett, Susan M. Hawes, Irene Tellis, Karen Koh, and Lihn Nguyen: Isolation and characterisation of human ES cells; 11: Sharon Gerecht-Nir and Joseph Itskovitz-Eldor: Differentiation of human ES cells; 12: Hirofumi Suemori, Yoshiki Sasai, Katsutsugu Umeda and Norio Nakatsuji: ES cell lines from the cynomolgus monkey (Macaca fascicularis); Index