Introduction, Mathematical Modelling and Computer Simulation, Process Control, Statistics for Treatment Plant Operation, The Use of Time Series Analysis in Hierarchical Control Systems, Computer Assisted Operation of the Kawamata Treatment Plant, Osaka Prefecture Japan, Application of Artificial Intelligence (AI) Techniques in Activated Sludge Process Design, Operations and Control, Knowledge Based (Expert) Systems for the Activated Sludge Process, Dynamic Modelling and Simulation of Large Scale Wastewater Treatment Plants Using The General Purpose Simulator.