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Diagnostic Techniques in Hematological Malignancies




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Dettagli

Genere:Libro
Lingua: Inglese
Pubblicazione: 11/2010





Note Editore

The diagnosis and monitoring of hematological malignancies is complex and requires a systematic approach. Morphology, cell phenotyping, cytogenetics and molecular genetics are essential, and the results must be integrated. Diagnostic Techniques in Hematological Malignancies details the principles and applications of each of these test types in the diagnosis of hematological malignancies in blood and bone marrow. The first section describes the test modalities – including methodological principles, data interpretation and limitations – and is illustrated by clinical examples. The second section focuses on the clinical entities, detailing the most appropriate tests for diagnosis, staging and monitoring of different hematological malignancies and includes test utilization to identify prognostic markers and potential therapeutic targets. With contributions from multiple international experts, this illustrated book is an essential resource for qualified and trainee hematologists, oncologists, and pathologists. It's a practical and useful guide, providing a rational and structured approach to the laboratory assessment of hematological malignancies.




Sommario

Preface; Part I. Diagnostic Techniques: 1. Morphology Wendy N. Erber; 2. Immunocytochemistry Wendy N. Erber; 3. Flow cytometry Maryalice Stetler-Stevenson and Constance M. Yuan; 4. Cytogenetics Christine J. Harrison and Claire Schwab; 5. Molecular genetics Ken Mills; Part II. Hematological Malignancies: 6. The integrated approach to the diagnosis of hematological malignancies Mike A. Scott and Wendy N. Erber; 7. Acute lymphoblastic leukemia Elaine Coustan-Smith and Dario Campana; 8. Acute myeloid leukemia David Grimwade; 9. Mature B cell leukemias Constantine S. Tam and Michael J. Keating; 10. Mature T cell and natural killer-cell leukemias Kaaren K. Reichard and Kathryn Foucar; 11. Lymphoma Jennifer Herrick and Ahmet Dogan; 12. Plasma cell neoplasms Rafael Fonseca and Riccardo Valdez; 13. Chronic myeloid leukemia Emma J. Gudgin and Brian Huntly; 14. Myeloproliferative neoplasms Philip A. Beer and Anthony R. Green; 15. Myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms Raphael Itzykson, Hervé Roudot and Pierre Fenaux; Index.




Prefazione

Diagnostic Techniques in Hematological Malignancies integrates the principles and applications of different laboratory test types in the diagnosis and monitoring of hematological malignancies in blood and bone marrow. With contributions from multiple international experts, this illustrated book is an essential resource for qualified and trainee hematologists, oncologists, and pathologists.




Autore

Wendy N. Erber MD, DPhil, FRCPA, FRCPath is Consultant Haematologist and Clinical Director of Haematology, Addenbrooke's Hospital, Cambridge, UK.










Altre Informazioni

ISBN:

9780521111218

Condizione: Nuovo
Dimensioni: 252 x 25 x 194 mm Ø 1100 gr
Formato: Copertina rigida
Illustration Notes:21 b/w illus. 306 colour illus. 75 tables
Pagine Arabe: 348


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