Dendritic Cells: Biophysics, Tumor Microenvironment and Chinese Traditional Medicine

In this book, the authors discuss the biophysical characteristics of Dendritic cells (DCs) at various differentiation stages and in tumor microenvironments in detail. A type of Chinese traditional herb, which can improve the biophysical and microrheological properties of DCs, is also introduced. DCs are potent and specialized antigen-presenting cells that play a crucial role in initiating and amplifying both the innate and adaptive immune responses. The biophysical and microrheological characteristics of DCs are important for their motility and normal immune function. In tumor microenvironments, the motility and immune functions of DCs are impaired, but the mechanisms are largely unknown. This book offers researchers a comprehensive and deep insight into the biophysical characteristics of DCs and may also help to improve the efficiency of anti-tumor therapy based on DCs.   

 

Summary.- Introduction.- The measurement protocols of cell biophysical characteristics.- Biophysical characteristics of dendritic cells at different differentiation stages.- Biophysical characteristics of dendritic cells in tumor microenvironment.- Effects of Chinese traditional herbs on dendritic cells.- Future perspectives

Zhu Zeng is a professor of the Department of Biotechnology, and the vice president of the School of Basic Medical Sciences, Guiyang Medical College. He was awarded as the distinguished young science and technology scholars of Guizhou Province in 2011. Since 2000, his main research interests focused on biophysical characteristics of dendritic cells.