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carel j.-c. (curatore); kelly paul a. (curatore) - deciphering growth

Deciphering Growth

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Dettagli

Genere:Libro
Lingua: Inglese
Pubblicazione: 08/2005
Edizione: 2005





Trama

Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. Evolution has been characterised by a dramatic increase in an organism’s body size, which is not only limited to the size of the brain.





Sommario

Evolutionary Trends in Body Size.- Sexual Dimorphism in the Growth of Homo sapiens: Facts, Inferences and Speculation.- Genetic Control of Size at Birth.- The GH/IGF-1 Axis: Insights from Animal Models.- Downstream Mechanisms of Growth Hormone Action.- Growth Hormone Receptor Signaling and Differential Actions in Target Tissues Compared to IGF-I.- IGF-I and Brain Growth: Multifarious Effects on Developing Neural Cells and Mechanisms of Action.- IGF-I Deficiency: Lessons from Human Mutations.- Putting IGF-I Biology into a Clinical Perspective.- IGF Resistance: The Role of the Type 1 IGF Receptor.- The Importance of the National Cooperative Growth Study (NCGS).- Why we are Treating Children with Growth Hormone: Lessons from the French Registry.










Altre Informazioni

ISBN:

9783540261926

Condizione: Nuovo
Collana: Research and Perspectives in Endocrine Interactions
Dimensioni: 235 x 155 mm
Formato: Copertina rigida
Illustration Notes:XIII, 155 p.
Pagine Arabe: 155
Pagine Romane: xiii


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