Computer-Aided Tissue Engineering

The recent revolution in the biological sciences and bioengineering, along with the advancements of modern design and manufacturing, biomaterials, biology, and biomedicine, have brought about the new field of computer-aided tissue engineering.  Advances in this fascinating new area of study encompass broad applications in large-scale tissue engineering fabrication, artificial organs, orthopaedic implants, and biological chips.  Computer-Aided Tissue Engineering highlights the interdisciplinary nature of this topic and reviews the current state of computer-aided three-dimensional tissue modeling, tissue classification, and tissue fabrication and implantation. Particular focus is placed on rapid prototyping and direct digital fabrication for cell and organs, construction of tissue analogs, and precursors to 3D tissue scaffolds.  Written for the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results.
 
Current and practical, Computer-Aided Tissue Engineering provides a coherent framework for researchers interested in these vital technologies and for clinicians who plan to implement them.

Computer-Aided Tissue Engineering: Benefiting from the Control Over Scaffold Micro-Architecture.- Computer-Aided Approach for Customized Cell-Based Defect Reconstruction.- A Novel Bone Scaffold Design Approach Based on Shape Function and All-Hexahedral Mesh Refinement.- Rapid Prototyping Composite and Complex Scaffolds with PAM^2.- Scaffold Pore Space Modulation Through Intelligent Design of Dissolvable Micro-Particles.- Scaffold Informatics and Biomimetic Design: Three-Dimensional Medical Reconstruction.- The Development of Computer-Aided System for Tissue Scaffolds (CASTS) System for Functionally Graded Tissue-Engineering Scaffolds.- Computer-Designed Nano-Fibrous Scaffolds.- A Neural Network Technique for Re-Meshing of Bone Micro-Structure.- Using the Taguchi Method to Obtain More Finesse to the Biodegradable Fibers.- Numerical Modeling in the Design and Evaluation of Scaffolds for Orthopaedic Applications.- Structural and Vascular Analysis of Tissue Engineering Scaffolds, Part 1: : Numerical Fluid Analysis.- Vascular and Structural Analysis of Tissue Engineering Scaffolds, Part 2: Topology Optimization.- Modeling of Bioreactor Hydrodynamic Environment and Its Effects on Tissue Growth.- Recent Advances in 3D Printing of Tissue Engineering Scaffolds.- Graft-Artery Junctions: Design Optimization and CAD Development.- Projection Printing of 3-Dimensional Tissue Scaffolds.- Laser Sintering for the Fabrication of Tissue Engineering Scaffolds.- Three-Dimensional Microfabrication by Two-Photon Polymerization Technique.- Direct Fabrication as a Patient Targeted Therapeutic in a Clinical Environment.- Microstereolithography-BasedComputer-Aided Manufacturing for Tissue Engineering.