Case Studies in Infectious Disease

Case Studies in Infectious Disease presents 40 case studies featuring the most important human infectious diseases worldwide. Fully revised and updated in this second edition, the book describes the natural history of infection from point of entry of the pathogen through to clinical management of the resulting disease or condition. A further 8 case studies have been provided online as supplementary material, and these can be downloaded by students. Five core sets of questions are posed in each case, with the answers covering the nature of the infectious agent, route(s) of spread and of infection, pathogenesis of disease, host response to infection, clinical manifestations, diagnosis, treatment and prevention. This standardized approach provides the reader with a logical basis for understanding these diverse and medically important organisms and diseases, fully integrating microbiology and immunology throughout. KEY FEATURES High-resolution photos accompany each case, from the causative agents of disease to the clinical manifestations of the infection. Exquisite artwork helps to illustrate important concepts throughout the book. Eight new cases added to this new edition, extending coverage of important infectious diseases of worldwide significance. A standardized set of core questions allows students to compare directly differences between microbes such as their structure, clinical manifestations, host response, pathogenesis and availability of vaccines. Questions and answers available online, test the reader’s understanding of each case study. The book provides essential case-based learning for undergraduate and graduate microbiology students, while medical students and trainee physicians will also find the up-to-date information on 48 globally important infectious diseases outlined in a clear, digestible form, invaluable during undergraduate studies and in future clinical practice.

Aspergillus fumigatus Borrelia burgdorferiand related species Campylobacter jejuni Candida albicans Chlamydia trachomatis Clostridiodiesdifficile Cytomegalovirus Echinococcusspp. Enteroviruses Epstein-Barr virus Escherichia coli Giardia lamblia Helicobacter pylori Hepatitis B virus Hepatitis C virus Herpes simplex virus Histoplasma capsulatum Human immunodeficiency virus Influenza virus Leishmaniaspp. Leptospiraspp. Listeria monocytogenes Mycobacterium leprae Mycobacterium tuberculosis Neisseria gonorrhoeae Neisseria meningitidis Norovirus Plasmodiumspp. Respiratory syncytial virus Rickettsiaspp. Salmonella typhi Schistosomaspp. Staphylococcus aureus Streptococcus pneumoniae Streptococcus pyogenes Toxoplasma gondii Trypanosomaspp. Trichophyton spp. and dermatophytesVaricella-zoster virus Wuchereria bancrofti Plus online cases: Bartonella bacilliformisBrucella Coxiella burnetti Dengue virusEnterococcus faecalis and E. faecium Mycobacterium abscessus SARS-CoV-2 Streptococcus mitis

Peter M Lydyard, Emeritus Professor of Immunology, University College Medical School, London, UK, Honorary Professor of Immunology, School of Life Sciences, University of Westminster, London, UK and Professor of Immunology, University of Georgia, Tbilisi, Georgia. Michael F Cole, Emeritus Professor of Microbiology and Immunology, Georgetown University Department of Microbiology & Immunology, Washington DC. USA. John Holton, Dept of Natural Sciences University of Middlesex London UK and Department of Pathology Darrent Valley Hospital Dartford UK. William L Irving, Professor and Honorary Consultant in Virology, University of Nottingham and Nottingham University Hospitals NHS Trust. Nina Porakishvili, Principal Lecturer in Life Sciences, University of Westminster, London, UK. Dr Pradhib Venkatesan, Consultant in Infectious Diseases, Department of Infectious Diseases, Nottingham University Hospitals City Campus, Nottingham. UK. Katherine N Ward, Honorary Professor, Division of Infection and Immunity, University College London, London, UK.