Breast Cancer Pathophysiology: An Interdisciplinary Approach

Breast cancer is one of the most prevalent malignancies worldwide, particularly in females, with a high rate of cancer-related deaths globally. Increasing age, obesity, harmful use of alcohol, family history of breast cancer, starting age of menstrual periods, and tobacco use are some of the risk factors for breast cancer.

The fifth volume of the “Interdisciplinary Cancer Research” series, entitled “Breast Cancer Pathophysiology: An Interdisciplinary Approach” publishes comprehensive volumes on the mechanisms of breast cancer, early detection, assessment, and patient outcome. The role of defective estrogen signals, membrane estrogen receptor, and dietary polyunsaturated fatty acids in breast cancer are also presented in this volume. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value to researchers, oncologists, and oncosurgeons who wish to extend their knowledge on breast cancer.

Interdisciplinary Approach in Breast Cancer.- Circulating Tumor Cells in Breast Cancer.- Breast Cancer Cells Extravasation Across the Blood-Brain Barrier: From Basic to Translational Research.- Turn in Breast Cancer Care: Upregulation of Estrogen Signal May Be Much More Effective than Its Inhibition.- Role of Membrane Estrogen Receptor (GPER1) on the Function of Immune Cells and Its Consequences on Breast Cancer Pathophysiology.- The Effect of Dietary n-3 Polyunsaturated Fatty Acids on Non-obese and Obesity-Associated Breast Cancer.- The Role of Soy and Its Isoflavones in Breast Cancer: Beneficial or Harmful?.- Mammographic Breast Density and Utility in Breast Cancer Screening and Clinical Decision-Making.- Advanced 3D In Vitro Models to Recapitulate the Breast Tumor Microenvironment.- Breast Cancer Metastasis to Bone: Look into the Future.- Breast Cancer: The Fight for Survival Is Won: What Is the Evidence for Preserving Fertility?.- Breast Cancer and Pregnancy: Challenges for Maternal and Newborn Successful Outcomes.- Computer-Aided Approach for BI-RADS Breast Density Classification: Multicentric Retrospective Study.- Correction to: Mammographic Breast Density and Utility in Breast Cancer Screening and Clinical Decision-Making.

Professor Nima Rezaei gained his medical degree (MD) from Tehran University of Medical Sciences and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital.  Professor Rezaei is now the Full Professor of Immunology and Vice Dean of Research and Technologies, School of Medicine, Tehran University of Medical Sciences, and the co-founder and Head of the Research Center for Immunodeficiencies. He is also the Founder of Universal Scientific Education and Research Network (USERN). Prof. Rezaei has already been the Director of more than two hundred research projects and has designed and participated in several international collaborative projects. Prof. Rezaei is the editor, editorial assistant, or editorial board member of more than fifty international journals. He has edited more than one hundred international books, has presented more than a thousand lectures/posters in congresses/meetings, and has published more than 1,500 scientific papers in the international journals.