Biotechnology and Bioinformatics Advances and Applications for Bioenergy, Bioremediation and Biopharmaceutical Research

Reflecting the interdisciplinary nature of biotechnology, this book covers the role of targeted delivery of polymeric nanodrugs to cancer cells, microbial detoxifying enzymes in bioremediation and bacterial plasmids in antimicrobial resistance. It addresses modern trends such as pharmacogenomics, evaluation of gene expression, recombinant proteins from methylotrophic yeast, identification of novel fermentation inhibitors of bioethanol production, and polyhydroxyalkanoate based biomaterials. The book highlights the practical utility of biotechnology and bioinformatics for bioenergy, production of high value biochemicals, modeling molecular interactions, drug discovery, and personalized medicine.

Preface Polymeric Nanoparticle Mediated Targeted Drug Delivery to Cancer Cells; Gul-E-Saba and Mohd Azmuddin Abdullah (Malaysia) Pharmacogenetics and Pharmacogenomics in Personalized Medicine: Role of Gene Polymorphism in Drug Response; Rownock Afruza, Fumiaki Suzuki, and A. H. M. Nurun Nabi (Bangladesh, Japan) Natural History and Molecular Biology of Hepatitis B Virus; Essam Mohammed Janahi (Kingdom of Bahrain) Reconfigurable Parallel Platforms for Dependable Personalized Health Monitoring; Olufemi Adeluyi and Jeong A. Lee (Republic of South Korea) High Throughput Evaluation of Gene Expression from Formalin-Fixed Paraffin-Embedded Tissues; Paraskevi A. Farazi (Cyprus) Microbial Detoxifying Enzymes Involved in Biodegradation of Organic Chemopollutants; Pradnya Pralhad Kanekar and Seema Shreepad Sarnaik (India) An Insight Into Horizontal Gene Transfer Triggering Widespread Antimicrobial Resistance in Bacteria; Zakir Hossain (Bangladesh) Production and Biotechnological Applications of Recombinant Proteins by Methylotrophic Yeast: Past, Present and Future Perspectives; Marcos López-Pérez and Rina María González-Cervantes (Mexico) Mechanism of Tolerance and Engineering of Yeast Strain Resistant to Novel Fermentation Inhibitors of Bioethanol Production; Lahiru Niroshan Jayakody, Nobuyuki Hayashi, and Hiroshi Kitagaki (Japan) Biotechnological Potential of Alkaliphilic Microorganisms; Pradnya Pralhad Kanekar, Amaraja Abhay Joshi, Snehal Omkar Kulkarni, Suchitra Baburao Borgave, Seema Shreepad Sarnaik, Smita Shrikant Nilegaonkar, Anita Satish Kelkar, and Rebecca Sandeep Thombre (India) Design and Tailoring of Polyhydroxyalkanoate-Based Biomaterials Containing 4-Hydroxybutyrate Monomer; Sevakumaran Vigneswari, Kesaven Bhubalan, and Abdullah Al-Ashraf Amirul (Malaysia) Algal Biotechnology for Bioenergy, Environmental Remediation and High-Value Biochemicals; Mohd Azmuddin Abdullah, Syed Muhammad Usman Shah, Ashfaq Ahmad, and Hamdy El-Sayed (Malaysia) Molecular Docking: A Practical Approach for Protein Interaction Analysis; Neil Andrew D. Bascos (Philippines) Application of Biotechnology and Bioinformatics in Drug Designing and Discovery; A. K. M. Mahbub Hasan, Sajib Chakrobarty, Rajib Chakrovorty, and A. H. M. Nurun Nabi (Australia, Bangladesh) Systems Biotechnology for Industrial Microorganisms; Ana M. Martins (United Arab Emirates) Bioinformatics and Biotechnology in Human Genetic Research: A Current Scenario; Sathiya Maran, Thirumulu Ponnuraj Kannan, and Teguh Haryo Sasongko (Malaysia) Index

Devarajan Thangadurai is senior assistant professor at Karnatak University in South India. He is also president of the Society for Applied Biotechnology; general secretary of the Association for the Advancement of Biodiversity Science; and journal editor-in-chief of several journals: Biotechnology, Bioinformatics and Bioengineering; Acta Biologica Indica; Biodiversity Research International; and Asian Journal of Microbiology. He received his PhD in botany from Sri Krishnadevaraya University in South India (2003). During 2002-2004, he worked as CSIR Senior Research Fellow with funding from the Ministry of Science and Technology, Government of India. He served as a postdoctoral fellow at the University of Madeira (Portugal), University of Delhi (India), and ICAR National Research Centre for Banana (India) from 2004 to 2006. He is the recipient of Best Young Scientist Award with Gold Medal from Acharya Nagarjuna University (2003) and the VGST-SMYSR Young Scientist Award of Government of Karnataka, Republic of India (2011). He has edited or authored 15 books, including Genetic Resources and Biotechnology (3 vols.), Genes, Genomes and Genomics (2 vols.) and Mycorrhizal Biotechnology, with publishers of national and international reputation. Jeyabalan Sangeetha earned his BSc in microbiology (2001) and PhD in environmental sciences (2010) from Bharathidasan University, Tiruchirappalli, Tamil Nadu, India. She also holds an MSc in environmental sciences (2003) from Bharathiar University, Coimbatore, Tamil Nadu, India. Between 2004 and 2008, she was the recipient of Tamil Nadu Government Scholarship and the Rajiv Gandhi National Fellowship of University Grants Commission, Government of India for her doctoral studies. She has published approximately 20 manuscripts detailing the effect of pollutants on the environment, and she has organized conferences, seminars, workshops, and lectures. Her main research interests are in the areas of environmental microbiology and environmentalbiotechnology, with particular emphasis on solid waste management, environmental impact assessment and microbial degradation of hydrocarbons. Her scientific and community leadership have included serving as an editor of the Journal of Biodiversity Research International, and acting secretary of the Society for Applied Biotechnology. Presently, she is the UGC Kothari Postdoctoral Fellow at Karnatak University in South India.