Basic Urological Sciences

A working knowledge of the basic sciences that underpin mechanisms of disease and the body’s response is widely recognised to be a critical part of urological training. This book is aimed at trainees to ensure they are up to date with this breadth of knowledge and it provides succinct summaries which are ideal for revising the basic sciences component of final assessments and examinations. The chapters cover anatomy and physiology, the basic principles of immunology and oncology and particular diseases. It is a compendium of "need to know" facts and is aimed at both FRCS (Urol) candidates and a wider gloabl surgical audience looking for an up to date summary.

List of contributors Abbreviations Preface Foreword SECTION I: BASIC MECHANISMS 1. Cellular and Immunobiology Masood Moghul, Sarah McClelland, and Prabhakar Rajan 2. Genetics Karl H. Pang and Saiful Miah 3. Oncogenesis and Metastasis Elizabeth Day and Hing Leung 4. Microbiology Katherine Belfield and Roger Bayston 5. Transplantation Jonathon Olsburgh and Rhana H. Zakri 6. Haemostasis and Thrombosis Karl H. Pang and Michael Laffan 7. Systemic Response to Surgery and Shock Nadir I. Osman SECTION II: EMBRYOLOGY, ANATOMY, AND PHYSIOLOGY 8. Embryology, Anatomy, and Physiology of the Kidneys and Ureters Paul Sturch, Sanjeev Madaan, and Seshadri Sriprasad 9. Embryology, Anatomy, and Physiology of the Adrenal Glands Karl H. Pang and Fausto Palazzo 10. Embryology, Anatomy, and Physiology of the Bladder Allan Johnston, Tarik Amer, Omar Aboumarzouk, and Hashim Hashim 11. Embryology, Anatomy, and Physiology of the Prostate Joseph Tam and Hashim Ahmed 12. Embryology, Anatomy, and Physiology of the Male Reproductive System Maria Satchi and Asif Muneer 13. Anatomical and Physiological Changes in Pregnancy Joanna Shepherd and Stephen Radley SECTION III: BENIGN PATHOLOGY 14. Pain Karl H. Pang and Sam H. Ahmedzai 15. Acute Kidney Injury and Chronic Kidney Disease Lynne Sykes, Ibrahim Ali, and Philip A. Kalra 16. Inflammation and Infection Judith Hall and Christopher K. Harding 17. Urolithiasis Jade Harrison and Ken Anson 18. Upper Urinary Tract Obstruction Sanjeev Pathak 19. Non-neurogenic Lower Urinary Tract Dysfunction Nadir I. Osman and Karl H. Pang 20. Neurogenic Lower Urinary Tract and Sexual Dysfunction Karl H. Pang. Nadir I. Osman, and Altaf Mangera 21. Penoscrotal Pathology Karl H. Pang and Majid Shabbir 22. Male Sexual Dysfunction and Male Factor Infertility Ian Eardley SECTION IV: MALIGNANT PATHOLOGY 23. Renal Cancer Sabrina H. Rossi and Grant D. Stewart 24. Urothelial and Urethral Cancer Ibrahim Jubber, Karl H. Pang, and James W.F. Catto 25. Prostate Cancer Karl H. Pang and James W.F. Catto 26. Testicular Cancer Selma Masic, Abhishek Srivastava, and Alexander Kutikov 27. Penile Cancer Eleni Anastasiadis and Nicholas A. Watkin SECTION V: THERAPEUTICS 28. Reconstruction Nadir I. Osman, Karl H. Pang, and Christopher R. Chapple 29. Pharmacology of the Lower Urinary Tract Pedro Abreu-Mendes, João Silva, and Francisco Cruz 30. Pharmacology of Male Sexual Function Andrei Kozan, Weida Lau, and Oliver Kayes 31. Antimicrobial Agents Thomas Webb, Karl H. Pang, and Ased Ali 32. Blood Products and Antithrombotics Karl H. Pang and Michael Laffan 33. Urological Cancer Agents Bernadett Szabados and Thomas Powles 34. External Beam Radiotherapy and Brachytherapy Sophia C. Kamran and Jason A. Efstathiou Index

Karl H. Pang MBChB, BSc, MSc, PhD, MRCSAcademic Urology Unit, University of SheffieldNadir I. Osman MBChB (Hons), PhD, FRCS(Urol)Department of Urology, Royal Hallamshire Hospital, SheffieldConsultantin Urological SurgeryProfessor James WF. Catto MBChB, PhD, FRCS(Urol)Academic Urology Unit, University of SheffieldProfessor of Urological Surgery and Honorary Consultant Urological Surgeon in pelvic oncology. Editor-in-chief European Urology JournalProfessor Christopher R. Chapple BSc, MBBS, MD, FRCS(Urol), FEBUDepartment of Urology, Royal Hallamshire Hospital, SheffieldHonorary Professor, University of Sheffield and Consultant Urological Surgeon in Reconstruction. European Urology Association Secretary General