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Antimalarial Natural Products

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Dettagli

Genere:Libro
Lingua: Inglese
Editore:

Springer

Pubblicazione: 01/2022
Edizione: 1st ed. 2022





Trama

This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine’s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine’s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature’s combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends byidentifying ten natural products with development potential as clinical antimalarial agents.




Sommario

Chapter 1. Antimalarial Natural Products.











Altre Informazioni

ISBN:

9783030898724

Condizione: Nuovo
Collana: Progress in the Chemistry of Organic Natural Products
Dimensioni: 235 x 155 mm
Formato: Copertina rigida
Illustration Notes:IX, 106 p. 112 illus., 8 illus. in color.
Pagine Arabe: 106
Pagine Romane: ix


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