Section 1 - Approach to the patient with respiratory failure; Respiratory physiology and pathophysiology - Dawn Fabbroni, Andrew Lumb; Diagnosis of respiratory failure - Colin Church, Giles Roditi, teve Banham,; Investigation of respiratory failure - Steve Banham, Giles Roditi, Colin Church,; The Microbiology laboratory - Marina Morgan; Clinical decision making - Martin Hughes, Graham Nimmo; Indications for ventilatory support - Rebecca Appelboam; ; Section 2 - Non-invasive treatment modalities; Oxygen therapy - Malcolm Sim, Martin Hughes, Roland Black; Non-invasive ventilation - William Kinnear; Continuous positive airways pressure - Ben Ivory, Roland Black; ; Section 3 - Invasive ventilation basics; Development of invasive ventilation - Julia Munn; Triggering and Cycling - Andrew Foo, Martin Hughes; Pressure vs volume delivery - Julius Cranshaw; Positive end expiratory pressure - Christopher Day; ; Section 4 - Invasive ventilation modes; Synchronized intermittent mandatory ventilation - David Muigai; Pressure control ventilation - Martyn Hawkins, Chris Cairns; Assist control ventilation - David Muigai; Pressure support ventilation - Martin Hughes, Roland Black; Airway pressure release ventilation and biphasic positive airway pressure - Martyn Hawkins, Paul McConnell; High-frequency oscillatory ventilation - Luigi Camporota; Software enhancements - Ben Ivory, Martin Hughes; Adaptive support ventilation - Brian Digby, Martin Hughes, Roland Black; Proportional assist ventilation - Eumorfia Kondili, Dimitris Georgopoulos; Neurally adjusted ventilatory assist - Christer Sinderby; Extracorporeal membrane oxygenation - Giles Peek; Adjuncts to ventilation - Tim Gould; ; Section 5 - The Ventilated Patient; Tracheal tubes - David Swann; Tracheostomy - Rebecca Appelboam; Humidification and suction - David Swann; Physiotherapy in intensive care units - Andrew Lockwood, Louise Watson; Monitoring on a ventilator - Peter MacNaughton, Mike Spivey; Complications of ventilation - Stuart McLellan, Graham Nimmo; Effects of mechanical ventilation on control of Breathing - Maria Klimathianaki, Dimitris Georgopolous; Patient ventilator asynchrony - Stefano Nava, Zuhal Karakurt; Heart-lung interactions - Michael Pinsky; Effects of mechanical ventilation on oxygenation - Martin Hughes, Roland Black; Hypercapnia while on a ventilator - Martin Hughes, Roland Black; Sudden deterioration on a ventilator - Roland Black, Martin Hughes; Sedation - Tim Walsh; Ventilation outside the intensive care unit - Alyson Calder, Alexander Binning; Weaning from mechanical ventilation - Ross Patterson, Ian Grant; Extubation - Ross Patterson, Ian Grant; Long-term (home) ventilation - Anthony Bateman, Ian Grant; Outcome and follow-up - John Griffiths, Brian Cuthbertson; ; Section 6 - Treatment of specific diseases; Acute respiratory distress syndrome - Timothy Fenton, Geoff Bellingan; Alveolar haemorrhage and pulmonary vasculitis - Lucy Smyth, Bipen Patel; Asthma - Graham Nimmo, Graham Douglas; Cardiogenic pulmonary oedema - Jonathan Dalzell, John McMurray; Conventional immune modifiers and biologic therapies - James Dale, Tom Evans, Iain McInnes; Chronic obstructive pulmonary disease - David Halpin; Drug-induced lung disease - Malcolm Booth; Extrapulmonary causes of respiratory failure - Andrew McDuff, Ian Grant; Haematological malignancy in ICU - Anthony Todd; Inhalational injury - John Kinsella; Interstitial lung disease - Nik Hirani; Pleural disease - Catherine Bateman, Nick Maskell; Pneumonia - Hugh Bakere, David Halpin; Respiratory disease in pregnancy - Rosemary Snaith, Elizabeth McGrady; Pulmonary embolism - Kevin Blyth; Pulmonary vascular disease - Martin Johnson, Nicola Lee; Thoracic surgical patients in ICU - Derek Paul, Ian Colquhoun; Thoracic trauma - Alasdair Dow; Miscellaneous lung disease - Nicola Lee, Martin Johnson;