3D Bioprinting in Regenerative Engineering Principles and Applications

Regenerative engineering is the convergence of developmental biology, stem cell science and engineering, materials science, and clinical translation to provide tissue patches or constructs for diseased or damaged organs. Various methods have been introduced to create tissue constructs with clinically relevant dimensions. Among such methods, 3D bioprinting provides the versatility, speed and control over location and dimensions of the deposited structures. Three-dimensional bioprinting has leveraged the momentum in printing and tissue engineering technologies and has emerged as a versatile method of fabricating tissue blocks and patches. The flexibility of the system lies in the fact that numerous biomaterials encapsulated with living cells can be printed. This book contains an extensive collection of papers by world-renowned experts in 3D bioprinting. In addition to providing entry-level knowledge about bioprinting, the authors delve into the latest advances in this technology. Furthermore, details are included about the different technologies used in bioprinting. In addition to the equipment for bioprinting, the book also describes the different biomaterials and cells used in these approaches. This text: Presents the principles and applications of bioprinting Discusses bioinks for 3D printing Explores applications of extrusion bioprinting, including past, present, and future challenges Includes discussion on 4D Bioprinting in terms of mechanisms and applications

1 Principles and applications of bioprinting . A. Skardal 2 Bioinks for 3D printing . E. Gargus, P. Lewis, and R. Shah 3 Applications of extrusion bioprinting: Past, present, future G. Forgacs, F. Marga, and K. Jakab 4 Laser-based 3D bioprinting Benjamin T. Vinson, S. C. Sklare, Yong Huang, and Douglas B. Chrisey 5 Inkjet-based 3D bioprinting Shibu Chameettachal and Falguni Pati 6 Rapid prototyping of soft bioactuators Caroline Cvetkovic, Eunkyung Ko, Collin Kaufman, Lauren Grant, Martha Gillette, Hyunjoon Kong, and Rashid Bashir 7 Bioprinting in otolaryngology and airway reconstruction David A. Zopf and Glenn E. Green 8 Bioprinting of human skin: Gaps, opportunities, and future directions Tania Baltazar, Carolina Catarino, and Pankaj Karande 9 Bioprinting vascular networks Vivian K. Lee and Guohao Dai 10 Bioprinting of living aortic valve D. Y. Cheung, S. Wu, B. Duan, and J. T. Butcher 11 3D bioprinting of cardiac muscle tissue Andrew Lee and Adam W. Feinberg 12 Additive manufacturing in the craniofacial area: Applications in vertical alveolar bone augmentation Cedryck Vaquette, Kelly McGowan, and Saso Ivanovski 13 Bioprinting of liver Dong-Woo Cho, Hyungseok Lee, Wonil Han, and Yeong-Jin Choi 14 Bioprinting-enabled technologies for cryopreservation Fariba Ghaderinezhad, Reza Amin, and Savas Tasoglu 15 4D bioprinting: Mechanism and applications Qingzhen Yang, Yuan Ji, and Feng Xu 16 Current challenges and future perspectives of bioprinting M. Varkey and A. Atala

Ali Khademhosseini is a Professor at Harvard Medical School and a faculty at the Harvard-MIT Division of Health Sciences and Technology, Brigham and Women's Hospital and as well as an Associate Faculty at the Wyss institute for Biologically Inspired Engineering. He also directs a satellite laboratory, the Advanced Institute for Materials Research at Tohuku University (Japan) He has authored over 400 peer-reviewed journal articles, editorials and review papers. In addition he has authored/edited ~60 book chapters and ~20 patent/disclosure applications.He has been recognized with over 30 major national and international awards. Dr. Camci-Unal is a postdoctoral fellow at Harvard University, with her research being at the interface of biomaterials and bioengineering with a particular emphasis on engineered platforms for cardiovascular amd bone tissue engineering. She has published over 50 peer reviewed journal articles, 34+ conference abstracs, and 4+ patent applications.