Oxford Textbook of Sjögren's Syndrome

Sjögren's syndrome is a chronic autoimmune disease which can cause debilitating fatigue and pain. Diagnosis is often challenging due to the variability of symptoms and severity, and a multidisciplinary approach to management and treatment is required, yet there are few comprehensive resources covering everything clinicians need to know. The Oxford Textbook of Sjögren's Syndrome bridges this gap by offering extensive coverage of system by system manifestations and treatments, as well as practical, evidence-based advice on diagnosing and managing this condition. Bringing together recent advances in research and therapies, this up-to-date guide covers everything clinicians need to know from the fundamental science and clinical characteristics of this condition, to the immunological and biochemical aspects, investigative procedures such as biopsy techniques and imaging modalities, and pharmacological and non-pharmacological interventions.

1.1 - Introduction
1.2 - Historical background, classification and diagnostic criteria
1.3 - Epidemiology and genetics of Sjögren s Syndrome
2.1 - Biomarkers in primary Sjögren sSyndrome
2.2 - Autoantibodies and autoantigens in Sjögren s Syndrome
2.3 - Stromal cells in Sjögren s Syndrome
3.1 - Clinical assessment of salivary glands function
3.2 - Biopsy gland biopsy procedure and histopathology
3.3 - Imaging in Sjögren s Syndrome
4.1 - Salivary glands manifestations and management
4.2 - Oral manifestations and management
4.3 - Dental related disease
5.1 - Ocular Manifestations of Sjögren s Syndrome
5.2 - A therapeutic strategy for Sjögren s Syndrome dry eye
6.1 - Cutaneous involvement and management of Sjögren s Syndrome
6.2 - Musculoskeletal disease - presentation and management
6.3 - Renal involvement in Primary Sjögren's Syndrome
6.4 - Gastrointestinal Disease in Sjögren s syndrome
6.5 - Neurological complications of Sjögren s Syndrome
6.6 - Cardiovascular and Lung Manifestations of Sjögren s Syndrome
6.7 - Haematological Manifestations of Sjögren s Syndrome
6.8 - Fatigue in Sjögren s Syndrome
6.9 - Non-pharmacological interventions for the management of Fatigue and Constitutional Symptoms in Sjögren s Syndrome
6.1 - Gynaecologic and obstetric aspects in Sjögren s Syndrome
6.11 - Sjögren s Syndrome Associated Lymphoma
7.1 - Juvenile and young adult onset Sjögren s Syndrome
8.1 - Mimics of Sjögren s Syndrome
8.2 - Sjögren s Syndrome overlaps
9.1 - Experimental therapies in primary Sjögren s Syndrome
9.2 - Sjögren s Syndrome Summary of Clinical Management

Dr Elizabeth J Price is a consultant rheumatologist who has a specific interest in Sjogren's Syndrome and runs a specialist Sjogren's clinic at the Great Western Hospital in Swindon. Her interest in Sjogren's dates from her Research Fellowship at The Kennedy Institute in London where she completed an MD thesis focusing on Sjogren's syndrome. She currently focuses on extraglandular manifestations of the disease and clinical research into SS and was the lead author and driving force behind the BSR Guidelines for the management of Sjogren's syndrome. Professor Anwar R Tappuni is a consultant in Oral Medicine with a special interest in the head and neck manifestations of Sjogren's syndrome. She leads a multidisciplinary clinic for Sjogren's syndrome patients at the Institute of Dentistry, Barts Health NHS Trust. Her team has produced impactful basic science and translational research, published in internationally renowned scientific journals. Professor Tappuni is the founder and director of the Doctorate in Clinical Dentistry in Oral Medicine programme at Queen Mary University of London. She was the lead author on the oral section of the NICE approved BSR Guidelines for the management of Sjogren's syndrome.