Neurology and Pregnancy Clinical Management

Pregnancy complicated by neurological disorders is a challenging area for both obstetricians and neurologists. Treatment of the maternal condition often needs to be adjusted because of concerns for the fetus, and some conditions have a major impact on the method, mode, and timing of delivery. Many of the clinical problems that arise in pregnant women with a neurological disease have not been the subject of clinical trials, so management must often be based on what published evidence is available and a good understanding of the likely interactions between the condition and pregnancy and vice versa. The editors and contributors represent a team with considerable experience in this area. They offer their "best practice" advice as how to treat the mother effectively, ensuring fetal safety, as well as embracing a philosophy that the pregnancy of a woman with a neurological disease should be made as enjoyable and rewarding for her as is possible.

ForewordNigel Leigh ForewordCatherine Nelson-Piercy Preface Editorial Note on the FDA Classification of Drugs and Pregnancy Contributors General Issues Neurogenetics and Pregnancy Dragana J. Josifova Imaging during PregnancyFrancessa Wilson and Jozef Jarosz Intrauterine Imaging, Diagnosis, and Intervention in Neurological DiseaseWilliam Dennes Disposition of Drugs in Pregnancy: Anti-Epileptic DrugsDave Berry Therapeutics and BreastfeedingThomas W. Hale Neuroanaesthesia in PregnancyJames Arden Neurocritical Care for the Pregnant WomanClemens Pahl Neurovascular Intervention during Pregnancy: Cerebral Aneurysms and Vascular MalformationsDaniel Walsh Analgesia and Anaesthesia in Neurological Disease and PregnancyJayaram K. Dasan Psychiatric and Neuropsychiatric Disorders in Pregnancy and the Post-Partum PeriodJohn Moriarty and Trudi Seneviratne Ethical and Legal IssuesHannah Turton and Peter Haughton Neurological Disease Pre-Eclampsia/Eclampsia and Peri-Partum ConvulsionsMichael S. Marsh Blackouts Arising in PregnancyRobert Delamont and Nicholas Gall Epilepsy and PregnancyLina A. M. Nashef, Nicholas Moran, Sara Lailey, and Mark P. Richardson Headache in PregnancyAnish Bahra Infections in PregnancyIskandar Azwa, Michael S. Marsh, and David A. Hawkins Idiopathic Intracranial HypertensionPaul Riordan-Eva Stroke in PregnancyVictoria A. Mifsud Vascular Malformations of the Brain in PregnancyDavid P. Breen, Catharina J. M. Klijn, and Rustam Al-Shahi Salman Pituitary Disease in PregnancyDorota Dworakowska and Simon J. B. Aylwin Neuro-Oncology in PregnancyFiona Harris, Sarah J. Jefferies, Rajesh Jena, Katherine E. Burton, Lorraine Muffett, and Neil G. Burnet Pregnancy and Movement DisordersYogini Naidu, Prashanth Reddy, and K. Ray Chaudhuri Multiple Sclerosis and PregnancyPeter A. Brex and Pauline Shaw Nutritional Deficiencies in PregnancyRoy A. Sherwood Spinal Disease and PregnancyMatthew Crocker and Nicholas Thomas Neurological Disability and PregnancyDavid N. Rushton Peripheral Nerve DiseasesRobert D. M. Hadden Muscle Disease and Myasthenia in PregnancyFiona Norwood Index

Michael Marsh, FRCOG, MD, Department of Obstetrics and Gynaecology, King’s College Hospital London, UK Lina Nashef, FRCP, MD, MBChB, Department of Neurology, King’s College Hospital London, UK Peter Brex, MRCP, Department of Neurology, King’s College Hospital London, UK