Biomedical Engineering Technologies Volume 1

This volume provides detailed technical protocols on current biosensors and imaging technologies and Chapters focus on optical, electrochemical, Quartz crystal microbalance (QCM) biosensors and on medical imaging technologies such as tomography, MRI, and NMR. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.

 

Authoritative and practical, Biomedical Engineering Technologies, Volume 1 provides technical details in descriptions of major technologies by experts in the field. 

1. A Compact Surface Plasmon Resonance Biosensor for Sensitive Detection of Exosomal Proteins for Cancer.- Electrochemistry Coupling Localized Surface Plasmon Resonance for Biochemical Detection.- Preparation of surface plasmon resonance aptasensor for human activated protein C sensing.- Large-scale nanogrooved photonic crystals for label-free biosensing by guided-mode resonance.- Plasmonic Nanoparticle Conjugation for Nucleic Acid Biosensing.- Ultrasensitive Label-Free Nucleic-Acid Biosensors Based on Bimodal Waveguide Interferometers.- Azimuthal Beam Scanning Microscope Design and Implementation for Axial Localization with Scanning Angle Interference Microscopy.- Computational Optics for Point-of-Care Breast Cancer Profiling.- DNA genotyping based on isothermal amplification and colorimetric detection by consumer electronics devices.- Evaluation of tumor development using hemoglobin saturation profile on rodent dorsal window chamber.- Automated multidimensional nanoscale chromatography for ultra-sensitive targeted mass spectrometry.- Clinical Translation of Stimulated Raman Histology.- Ex vivo and in vitro methods for detection of bioactive staphylococcal enterotoxins.- An Ultracompact Real-time Fluorescence Loop-mediated Isothermal Amplification (LAMP) Analyzer.- Digital Quantification of Human Viral RNA and DNA using a Self-Digitization Chip.- Sample-to-Answer Microfluidic Nucleic Acid Testing (NAT) (file #on Lab-on-a-Disc for Malaria Detection at Point-of-Need.- Charge sensitive optical detection for measurement of small molecule binding kinetics.- Mobile Elisa With A Transparent Incubator.- Smartphone Enabled Point-of-Care Detection of Serum Biomarkers.- Micromachined Optical Fiber Sensors for Biomedical Applications.- Optical and electrochemical aptasensors for sensitive detection of aflatoxin B1 and aflatoxin M1 in blood serum, grape juice and milk samples.- DNA Generated Electric Current Biosensor for Epidermal Growth Factor Receptor 2 (HER2) Analysis.- Agar-Integrated Three-Dimensional Microelectrodes for On-Chip Impedimetric Monitoring of Bacterial Viability.- Quantitative and selective DNA detection with portable personal glucose meter using loop-based DNA competitive hybridization strategy.- Electrochemical aptamer-based sensors: a platform approach to high frequency molecular monitoring in situ in the living body.- Smartphone-based Electrochemical System for Biosensors and Biodetection.- Preparation of notch-4 receptor containing quartz crystal microbalance biosensor for MDA MB 231 cancer cell detection.-The study of the skin cells viscoelastic changes using QCM-D measurements.- Hyperpolarized micro-NMR platform for sensitive analysis of in vitro metabolic flux in living cells.- Mixed Modeling Frameworks for Analyzing Whole-Brain Network Data.- Rapid In Vivo Quantification of Creatine Kinase Activity by Phosphorous-31 Magnetic Resonance Spectroscopic Fingerprinting (31P-MRSF).- Nanoparticle assisted nuclear relaxation-based detection of oligonucleotides.- Imaging Biomarker Development for Lower Back Pain using Machine Learning.- Acoustic Angiography: Superharmonic Contrast-Enhanced Ultrasound Imaging for Non-Invasive Visualization of Microvasculature.- Patch Clamp Technology for Focused Ultrasonic (FUS) (file #Neuromodulation.- Wireless Wearable Ultrasound Sensor to Characterize Respiratory Behavior.- Forming large effective ultrasound arrays using the swept synthetic aperture technique.- Quantitative bioluminescence tomography for in vivo volumetric-guided radiotherapy.- Evaluation of pulmonary structure and function in patients with cystic fibrosis from electrical impedance tomography data.- In-Vivo Quantitative Whole-Body Perfusion Imaging Using Radiolabeled Copper(II) (file #bis(thiosemicarbazone) (file #Complexes and Positron Emission Tomography (PET).- Biodegradable AuNP-based plasmonic nanogels as contrast agents for computed tomography and photoacoustics.- Cationic Contrast Agents for Computed Tomographyof Cartilage for Early Diagnosis of Osteoarthritis.- Economical production of radiopharmaceuticals for preclinical imaging using microdroplet radiochemistry.- Preparation of radiolabeled antibodies for nuclear medicine applications in immuno-oncology.- A Wireless Fully-Passive Acquisition of Biopotentials.- Fabrication of Skin-Mountable Flexible Sensor Patch for Monitoring of Swallowing Function.- The Intelligent Phenotypic Plasticity Platform (IP3) (file #for Precision Medicine-based Injury Prevention in Sport.