The Dynamic Genome and Mental Health

NOTE EDITORE

While it is widely accepted that we are products of our genes and environment, misconceptions about the power of genes to control our destiny continue to dominate our discourse. This volume contains the latest theories and evidence supporting the highly dynamic inter-relation between genes and environments as they influence the development, mental health, and substance use of adolescents. Written by researchers who are leading the way toward this new understanding, this text provides overviews and analysis of this emerging field. The chapters discuss the latest approaches to gene-environment relations, including gene-environment interaction, gene-environment correlation, epigenetics, and environmental regulation of gene expression. The application of these concepts to the prevention of adolescent mental health conditions, such as drug use, conduct disorder, depression, and schizophrenia, is included. Controversies in the implications of these approaches are also discussed. The chapters are written in accessible language and will relevant to anyone interested in the mental health and development of adolescents, including researchers and practitioners in behavioral, social and medical fields. A final chapter by the editors assesses the implications of these new approaches for future mental health research and policy.

SOMMARIO

1. - A Conceptual Overview of Gene-Environment Interaction and Correlation in a Developmental Context2. - Gene-Environment Interactions3. - Improving Environmental Markers in Gene-Environment Research: Insights from Life Course Sociology4. - Genotype-Environment Correlations: Definitions, Methods of Measurement, and Implications for Research on Adolescent Psychopathology5. - The Social Dynamics of the Expression of Genes for Cognitive Ability6. - Family Relationship Influences on Development: What Can We Learn from Genetic Research?7. - Epigenetic Effects on Gene Function and their Role in Mediating Gene-Environment Interactions8. - Integrating Knowledge of Genetic and Environmental Pathways to Complete the Developmental Map9. - Socio-Environmental Effects on Gene Expression10. - . The Interplay between Genes and Environment in Anxiety and Depression11. - Adolescence and Risk for Anxiety and Depression: Insights from Human Imaging to Mouse Genetics12. - Genetic and Environmental Predictors of Depression13. - Genes, Environment, and Adolescent Smoking: Implications for Prevention14. - The Dynamic Nature of Genetic and Environmental Influences on Alcohol Use and Dependence15. - The Importance of Understanding Gene-Environment Correlations in the Development of Antisocial Behavior16. - Peer group deviance, conduct disorder and alcohol intake17. - Stress Hormones, Genes, and Neuronal Signaling In Adolescence: The Perfect Storm for Vulnerability to Psychosis18. - The Role of Stress and its Interaction with Genetic Predisposition in Schizophrenia19. - Conclusions and Implications for the Future

AUTORE

Kenneth S. Kendler, MD, is Professor of Psychiatry and Human and Molecular Genetics at Virginia Commonwealth University and Director of the Virginia Institute for Psychiatric and Behavioral Genetics Sarah Jaffee, PhD, is a Developmental Psychopathologist at Kings College, London Daniel Romer, PhD, is Dan Romer is director of the Adolescent Communication Institute (ACI) of the Annenberg Public Policy Center at the University of Pennsylvania

ALTRE INFORMAZIONI

• Condizione: Nuovo
• ISBN: 9780199737963
• Dimensioni: 155 x 22.9 x 231 mm Ø 680 gr
• Formato: Brossura
• Pagine Arabe: 480