Reprogramming Microbial Metabolic Pathways

TRAMA

Metabolic engineering has been developed over the past 20 years to become an important tool for the rational engineering of industrial microorganisms. This book has a particular interest in the methods and applications of metabolic engineering to improve the production and yield of a variety of different metabolites. The overall goal is to achieve a better understanding of the metabolism in different microorganisms, and provide a rational basis to reprogram microorganisms for improved biochemical production.

SOMMARIO

Contributors  Part I: Emerging Methods for Redesigning Microorganisms1. Towards Synthetic Gene Circuits with Enhancers: Biology's Multi-input Integrators; Roee Amit2. Elementary Mode Analysis: A Useful Metabolic Pathway Analysis Tool for Reprograming Microbial Metabolic Pathways; Cong T. Trinh and R. Adam Thompson3. Evolutionary Engineering for Industrial Microbiology; Niti Vanee, Adam B. Fisher and Stephen S. Fong4. Monitoring Microbial Diversity of Bioreactors Using Metagenomic Approaches; Joshua T. Ellis, Ronald C. Sims and Charles D. Miller5. Synthetic Biology Triggers New Era of Antibiotics Development; Jianfeng Wang, Zhi-Qiang Xiong, Hailin Meng, Yiguang Wang and Yong Wang6. Cascades and Networks of Regulatory Genes That Control Antibiotic Biosynthesis; Juan F. Martín and Paloma Liras7. Systems Analysis of Microbial Adaptations to Simultaneous Stresses; Ross P. Carlson, Olusegun J. Oshota and Reed L. Taffs8. Metabolic Reprogramming under Microaerobic and Anaerobic Conditions in Bacteria; Yue Shan, Yong Lai and Aixin Yan9. Tunable Promoters in Synthetic and Systems Biology; Tore Dehli, Christian Solem and Peter Ruhdal Jensen10. Analysis of Corynebacterium glutamicum Promoters and Their Applications; Jan Nešvera, Jirí Holátko and Miroslav PátekPart II: Metabolic Engineering for Overproducing Chemicals and Materials11. Production of Fumaric Acid by Fermentation; Adrie J.J. Straathof and Walter M. van Gulik12. Metabolic Engineering of Microorganisms for Vitamin C Production; Jingwen Zhou, Guocheng Du and Jian Chen13. Molecular Mechanisms and Metabolic Engineering of Glutamate Overproduction in Corynebacterium glutamicum; Takashi Hirasawa, Jongpill Kim, Tomokazu Shirai, Chikara Furusawa and Hiroshi Shimizu14. Microbial Metabolic Engineering for L-threonine Production; Xunyan Dong, Peter J. Quinn and Xiaoyuan Wang15. The Production of Coenzyme Q10 in Microorganisms; Corinne P. Cluis, Dominic Pinel and Vincent J. Martin16. Genetic Modification and Bioprocess Optimization for S-adenosyl-L-methionine biosynthesis; Xiaoqing Hu, Peter J. Quinn, Zhou Wang, Guoqiang Han and Xiaoyuan Wang17. Manipulation of Ralstonia eutropha Carbon Storage Pathways to Produce Useful Bio-based Products; Christopher J. Brigham, Natalia Zhila, Ekaterina Shishatskaya, Tatiana G. Volova and Anthony J. Sinskey18. Metabolic Engineering of Inducer Formation for Cellulase and Hemicellulase Gene Expression in Trichoderma reesei; Bernhard Seiboth, Silvia Herold and Christian P. Kubicek19. Microbiologically Produced Carboxylic Acids Used as Building Blocks in Organic Synthesis; Andreas Aurich, Robert Specht, Roland A. Müller, Ulrich Stottmeister, Venelina Yovkova, Christina Otto, Martina Holz, Gerold Barth, Philipp Heretsch, Franziska A. Thomas, Dieter Sicker and Athanassios Giannis Index Index

ALTRE INFORMAZIONI

• Condizione: Nuovo
• ISBN: 9789400792432
• Collana: Subcellular Biochemistry
• Dimensioni: 235 x 155 mm Ø 694 gr
• Formato: Brossura
• Illustration Notes: XIV, 442 p.
• Pagine Arabe: 442
• Pagine Romane: xiv