MicroRNA Profiling in Cancer

NOTE EDITORE

This book presents advances in the interdisciplinary field of microRNA research of human cancers from a unique perspective of quantitative sciences: bioinformatics, computational and systems biology, and mathematical modeling. This volume contains adaptations and critical reviews of state-of-the-art studies, ranging from technological advances in microRNA detection and profiling, clinically oriented microRNA profiling in several human cancers, to a systems biology analysis of global patterns of microRNA regulation of signaling and metabolic pathways. It discusses interactions with transcription factor regulatory networks and mathematical modeling of microRNA regulation.

SOMMARIO

Measurement and Interpretation of MiRNA Expression Profiles MicroRNA Expression Analysis by LNA Enhanced Microarrays Analysis and QC for Real-Time QPCR Arrays of Human MicroRNAs Massively Parallel MicroRNA Profiling in the Haematologic Malignancies Who Dunit? MicroRNAs Involved in Prostate Cancer Intronic MicroRNA Creation, Evolution and Regulation Mirome Architecture and Genomic Instability Interconnection of MicroRNA and Transcription Factor-Mediated Regulatory Networks Analysis of MicroRNA Profiling Data with Systems Biology Tools Mathematical and Computational Modeling of Post-Transcriptional Gene Regulation by MicroRNAs

AUTORE

Yuriy Gusev, PhD, assistant professor in Bioinformatics, Department of Surgery, at the University of Oklahoma Health Sciences Center, is instrumental in the ongoing development and activities of a surgical research facility focused on molecular and cellular studies of human diseases related to surgery. He is responsible for the management of computerized cell imaging and bioinformatics systems for gene expression micro-arrays technologies in Surgical Research Core Facilities as well as the education of residents, postdoctoral fellows, and medical and graduate students.

ALTRE INFORMAZIONI

• Condizione: Nuovo
• ISBN: 9789814267014
• Dimensioni: 9.25 x 6.25 in Ø 1.42 lb
• Formato: Copertina rigida
• Illustration Notes: 6 b/w images and 41 color images
• Pagine Arabe: 257