Chimerism

TRAMA

This text provides a comprehensive, up-to-date review of chimerism. The first part of the volume presents the causes of chimerism, specifically focusing on fertilization and early embryonic errors, pregnancy and multiple gestations, and transplantation and transfusion. The second part of the volume outlines clinical identification and consequences of chimerism. Chapters in this section focus on the effects of chimerism on testing in relationship determination and forensics, prenatal genetic testing and screening, and blood and HLA typing. This part also reviews new data concerning matching donors and recipients for transplantation, while outlining the risks of transplantation, such as graft-vs-host disease and passenger lymphocyte syndrome.  Additionally, evidence on the role of chimerism in autoimmune disease and cancer is presented.  Written by experts in the field, Chimerism: A Clinical Guide is a valuable resource for clinicians and researchers that will help guide patient management and stimulate investigative efforts.

SOMMARIO

Part I: Causes of Chimerism in HumansChapter 1: Fertilization and Early Embryonic ErrorsNicole L. Draper, Kristy Crooks Chapter 2: Pregnancy and Multiple GestationsLinda Marie Randolph, Ramen H. Chmait Chapter 3: Transplantation and TransfusionJoel N. Kniep Part II: Clinical Identification and Consequences of ChimerismChapter 4: Relationship Testing and Forensics Kayla Sheets, Robert WenkChapter 5: Prenatal Genetic Testing and ScreeningIgnatia B. Van den VeyverChapter 6: Blood Typing DiscrepanciesOpal L. Reddy, Dawn C. Ward, Andrea M. McGonigleChapter 7: Hematopoietic Stem Cell Donor Selection and Graft-Versus-Host DiseaseAlexa J. Siddon, Christopher A. TormeyChapter 8: Passenger Lymphocyte SyndromeNicole L. Draper, Jamie E. KallanChapter 9: Chimerism: A Clinical Guide to Tolerance InductionAndrea R. Merchak, Anita Chhabra, Joseph Leventhal, Suzanne T. IldstadChapter 10: Autoimmune DiseaseNathalie Lambert Chapter 11: CancerValentina Cirello, Laura Fugazzola

AUTORE

Nicole L. Draper, MDUniversity of Colorado School of MedicineDepartment of PathologyAurora, CO USA

ALTRE INFORMAZIONI

• Condizione: Nuovo
• ISBN: 9783319898650
• Dimensioni: 235 x 155 mm Ø 3187 gr
• Formato: Copertina rigida
• Illustration Notes: XI, 200 p. 20 illus., 15 illus. in color.
• Pagine Arabe: 200
• Pagine Romane: xi