Pathogens Associated with the Development of Cancer in Humans OMICs, Immunological, and Pathophysiological Studies

This book examines the relationship between the different infectious agents, such as viruses, bacteria, protozoa, and fungi, in the development of cancer. It is divided into six sections, spanning a range of topics, including infectious agents, main bacterial agents, and eukaryotic microorganisms, and how they contribute to cancer. Chapters also explore the anti-tumor effect of microorganisms, how pathogens induce epigenetic changes that are associated with cancer, and nutritional management for the prevention and treatment of pathogen-associated cancer, from a nutrigenomics perspective. The studies included cover epidemiological and immunological data, different OMICs data in general, and data of pathogens associated with cancer. The book is rounded out with an analysis of the role of glycans and molecular evolution in the progression of cancer. 

The Role of Pathogens Associated with Hu-man Cancer and the Concept of Omics: An Overview.- Progression Pathways of Human Papilloma-virus-Associated Cancer.- Virus Hepatitis B virus and Hepatocellular Cancer: Molecular Mechanisms and Breakthroughs in Therapeutic Approaches.- Hepatitis C virus and Hepatocellular Cancer: Molecular Mechanisms and Advancements in Treatment.- Polyomaviruses in Human Cancers: a Com-plex Interplay Between Environmental, Cellular, and Viral Factors.- Epstein-Barr Virus: A Novel Dimension in Cancer Development.- Human Herpesvirus 8: Kaposi Sarcoma-Associated Virus.- Human Immunodeficiency Virus.- The Retrovirus Human T-cell Leukemia Virus Type 1 (HTLV-1).- Helicobacter pylori: Its Significance in the Pathogenesis of Gastric Malignancies.- Toxoplasma gondii and its Relation to Cancer.- Trichomonas vaginalis and Cancer: its Role in Cervical and Prostate Cancer Development.- Clonorchis sinensis and Carcinogenesis Risk: Biomarkers and Underlying Pathways.- Schistosoma haematobium, a Pathophysiological Review from Chronic Infection to Bladder Cancer.- Antitumor Effect Induced by Protozoa and Helminth Infections: Current Trends and Future perspectives.- Mycology in Oncology: Exploring the Role of the Mycobiome in Human Cancer, Etiology, Progression, Epidemiology, Mycoses, and Mycotoxins.- Cancer Induction by Microbial Metabolites and Toxins.- Natural Compounds for Inhibiting Onco-genic Microbiota: A Review of Their Therapeutic Applications.- Epigenetic Changes Induced by Infectious Agents in Cancer.- Nutrigenomics and its Relationship with Pathogens Associated with Cancer.- Glycobiology of Cancer.- Pathogen-Induced Glycosylation Alterations: Untangling the Host Cell's Sweet Response.- The Genomics Evolutionary of Cancer-Associated Pathogens.

Noé Velázquez-Marquez has been a professor at the Department of Microbiology and Parasitology at the Universidad de la Salud del Estado de Puebla (USEP) since 2020 and has been a professor at the Department of Cell Biology at the Benemérita Universidad Autónoma de Puebla (BUAP) since 2011. He obtained his Doctorate in Sciences in Microbiology at BUAP in 2009 and did postdoctoral studies at the Eastern Biomedical Research Center of the Mexican Institute of Social Security (CIBIOR-IMSS) in 2011. Dr. Velázquez worked with molecular diagnosis of HPV, cervical cancer, and the role of viral oncoproteins E6 and E7 in inducing changes in glycosylation patterns. He serves as a professor-researcher in the Faculty of Medicine at BUAP and USEP. His teaching responsibilities encompass Microbiology and Cellular and Molecular Biology across undergraduate, graduate, and specialty programs. He also directs and co-directs theses from master and specialty students.

Genaro Alberto Paredes-Juárez studied his PhD at the University of Groningen with a degree in Biomedical Engineering (2015), posteriorly he did a postdoctoral internship at Johns Hopkins School of Medicine at the department of Radiology and Imaging (2015-2017). His main interest is the research for using biomaterials as vehicles for a controlled released of substances, from chemicals to cellular products in the treatment of several diseases or concomitantly with other therapies. He was an invited professor at the Universidad Popular Autónoma del Estado de Puebla (UPAEP, 2019). He also dictates several courses to undergraduate and graduate students and directs and co-directs theses from master and PhD students. He belongs to the Mexican National System of Researchers (SNI 1) from CONAHCYT since 2020.

Verónica Vallejo-Ruiz is principal investigator of the Molecular Laboratory, East Biomedical Research Center of the Mexican Institute of Social Security.She earned his PhD at the Université des Sciences et Technologies de Lille, France (2001). She has served as director of graduate programs at the Benemérita Universidad Autónoma de Puebla, Universidad Nacional Autónoma de México and at the Universidad Popular Autónoma de Puebla. Dr. Vallejo-Ruiz works specializes on cervical cancer particularly with the glycobiology and genetic regulation of glycogenes and on the epidemiology of human papillomavirus.